rs80359377

plus

Geno	Mag	Summary
(-;A)	6	BRCA2 variant considered pathogenic for breast cancer
(A;A)	0	common in clinvar

Make rs80359377(-;-)

Reference

GRCh38 38.1/141

Chromosome

13

Position

32337554

Gene

BRCA2

is a	snp
is	mentioned by
dbSNP	rs80359377
dbSNP (classic)	rs80359377
ClinGen	rs80359377
ebi	rs80359377
HLI	rs80359377
Exac	rs80359377
Gnomad	rs80359377
Varsome	rs80359377
LitVar	rs80359377
Map	rs80359377
PheGenI	rs80359377
Biobank	rs80359377
1000 genomes	rs80359377
hgdp	rs80359377
ensembl	rs80359377
geneview	rs80359377
scholar	rs80359377
google	rs80359377
pharmgkb	rs80359377
gwascentral	rs80359377
openSNP	rs80359377
23andMe	rs80359377
SNPshot	rs80359377
SNPdbe	rs80359377
MSV3d	rs80359377
GWAS Ctlg	rs80359377

Max Magnitude

6

rs80359377, also known as 3427delA, c.3199_3199delA and p.Thr1067Leufs, is a variant in the BRCA2 gene considered pathogenic for breast cancer in ClinVar.

ClinVar
Risk	rs80359377(-;-)
Alt	rs80359377(-;-)
Reference	Rs80359377(A;A)
Significance	Pathogenic
Disease	Hereditary breast and ovarian cancer syndrome Breast-ovarian cancer not provided
Variation	info
Gene	BRCA2
CLNDBN	Hereditary breast and ovarian cancer syndrome Breast-ovarian cancer, familial 2 not provided
Reversed	0
HGVS	NC_000013.10:g.32911691delA
CLNSRC	Breast Cancer Information Core (BRCA2)
CLNACC	RCV000044145.3, RCV000077296.5, RCV000483265.1,