rs80359401

plus

Geno	Mag	Summary
(-;A)	6	BRCA2 variant considered pathogenic for breast cancer
(A;A)	0	common in clinvar

Make rs80359401(-;-)

Reference

GRCh38 38.1/141

Chromosome

13

Position

32338072

Gene

BRCA2

is a	snp
is	mentioned by
dbSNP	rs80359401
dbSNP (classic)	rs80359401
ClinGen	rs80359401
ebi	rs80359401
HLI	rs80359401
Exac	rs80359401
Gnomad	rs80359401
Varsome	rs80359401
LitVar	rs80359401
Map	rs80359401
PheGenI	rs80359401
Biobank	rs80359401
1000 genomes	rs80359401
hgdp	rs80359401
ensembl	rs80359401
geneview	rs80359401
scholar	rs80359401
google	rs80359401
pharmgkb	rs80359401
gwascentral	rs80359401
openSNP	rs80359401
23andMe	rs80359401
SNPshot	rs80359401
SNPdbe	rs80359401
MSV3d	rs80359401
GWAS Ctlg	rs80359401

Max Magnitude

6

rs80359401, also known as 3945delA, c.3717_3717delA and p.Lys1239Asnfs, is a variant in the BRCA2 gene considered pathogenic for breast cancer in ClinVar.

ClinVar
Risk	rs80359401(-;-)
Alt	rs80359401(-;-)
Reference	Rs80359401(A;A)
Significance	Pathogenic
Disease	Breast-ovarian cancer Hereditary breast and ovarian cancer syndrome Hereditary cancer-predisposing syndrome Familial cancer of breast not provided
Variation	info
Gene	BRCA2
CLNDBN	Breast-ovarian cancer, familial 2 Hereditary breast and ovarian cancer syndrome Hereditary cancer-predisposing syndrome Familial cancer of breast not provided
Reversed	0
HGVS	NC_000013.10:g.32912209delA
CLNSRC	Breast Cancer Information Core (BRCA2)
CLNACC	RCV000031436.9, RCV000044250.4, RCV000132471.2, RCV000464504.1, RCV000486579.1,