rs80359408

plus

Geno	Mag	Summary
(-;AA)	6	BRCA2 variant considered pathogenic for breast cancer
(AA;AA)	0	common in clinvar

Make rs80359408(-;-)

Reference

GRCh38 38.1/141

Chromosome

13

Position

32338214

Gene

BRCA2

is a	snp
is	mentioned by
dbSNP	rs80359408
dbSNP (classic)	rs80359408
ClinGen	rs80359408
ebi	rs80359408
HLI	rs80359408
Exac	rs80359408
Gnomad	rs80359408
Varsome	rs80359408
LitVar	rs80359408
Map	rs80359408
PheGenI	rs80359408
Biobank	rs80359408
1000 genomes	rs80359408
hgdp	rs80359408
ensembl	rs80359408
geneview	rs80359408
scholar	rs80359408
google	rs80359408
pharmgkb	rs80359408
gwascentral	rs80359408
openSNP	rs80359408
23andMe	rs80359408
SNPshot	rs80359408
SNPdbe	rs80359408
MSV3d	rs80359408
GWAS Ctlg	rs80359408

Max Magnitude

6

rs80359408, also known as 4087delAA, c.3859_3860delAA and p.Asn1287Terfs, is a variant in the BRCA2 gene considered pathogenic for breast cancer in ClinVar.

ClinVar
Risk	rs80359408(-;-)
Alt	rs80359408(-;-)
Reference	Rs80359408(AA;AA)
Significance	Pathogenic
Disease	Familial cancer of breast Breast-ovarian cancer Hereditary cancer-predisposing syndrome
Variation	info
Gene	BRCA2
CLNDBN	Familial cancer of breast Breast-ovarian cancer, familial 2 Hereditary cancer-predisposing syndrome
Reversed	0
HGVS	NC_000013.10:g.32912351_32912352delAA
CLNSRC	Breast Cancer Information Core (BRCA2)
CLNACC	RCV000044286.2, RCV000113228.2, RCV000216461.1,