rs80359412

plus

Geno	Mag	Summary
(-;AAAT)	6	BRCA2 variant considered pathogenic for breast cancer
(AAAT;AAAT)	0	common in clinvar
(AATA;AATA)	0	common in clinvar

Make rs80359412(-;-)

Reference

GRCh38 38.1/141

Chromosome

13

Position

32338220

Gene

BRCA2

is a	snp
is	mentioned by
dbSNP	rs80359412
dbSNP (classic)	rs80359412
ClinGen	rs80359412
ebi	rs80359412
HLI	rs80359412
Exac	rs80359412
Gnomad	rs80359412
Varsome	rs80359412
LitVar	rs80359412
Map	rs80359412
PheGenI	rs80359412
Biobank	rs80359412
1000 genomes	rs80359412
hgdp	rs80359412
ensembl	rs80359412
geneview	rs80359412
scholar	rs80359412
google	rs80359412
pharmgkb	rs80359412
gwascentral	rs80359412
openSNP	rs80359412
23andMe	rs80359412
SNPshot	rs80359412
SNPdbe	rs80359412
MSV3d	rs80359412
GWAS Ctlg	rs80359412

Max Magnitude

6

rs80359412, also known as 4093del4, c.3865_3868delAAAT and p.Lys1289_Cys1290?fs, is a variant in the BRCA2 gene considered pathogenic for breast cancer in ClinVar.

23andMe name: i5009157

ClinVar
Risk	rs80359412(-;-)
Alt	rs80359412(-;-)
Reference	Rs80359412(AATA;AATA)
Significance	Pathogenic
Disease	Breast-ovarian cancer Hereditary breast and ovarian cancer syndrome Hereditary cancer-predisposing syndrome not provided
Variation	info
Gene	BRCA2
CLNDBN	Breast-ovarian cancer, familial 2 Hereditary breast and ovarian cancer syndrome Hereditary cancer-predisposing syndrome not provided
Reversed	0
HGVS	NC_000013.10:g.32912357_32912360delAAAT
CLNSRC	Breast Cancer Information Core (BRCA2)
CLNACC	RCV000031443.8, RCV000044292.3, RCV000216772.1, RCV000412719.1,