rs80359459

plus

Geno	Mag	Summary
(-;AA)	6	BRCA2 variant considered pathogenic for breast cancer
(AA;AA)	0	common in clinvar

Make rs80359459(-;-)

Reference

GRCh38 38.1/141

Chromosome

13

Position

32326137

Gene

BRCA2

is a	snp
is	mentioned by
dbSNP	rs80359459
dbSNP (classic)	rs80359459
ClinGen	rs80359459
ebi	rs80359459
HLI	rs80359459
Exac	rs80359459
Gnomad	rs80359459
Varsome	rs80359459
LitVar	rs80359459
Map	rs80359459
PheGenI	rs80359459
Biobank	rs80359459
1000 genomes	rs80359459
hgdp	rs80359459
ensembl	rs80359459
geneview	rs80359459
scholar	rs80359459
google	rs80359459
pharmgkb	rs80359459
gwascentral	rs80359459
openSNP	rs80359459
23andMe	rs80359459
SNPshot	rs80359459
SNPdbe	rs80359459
MSV3d	rs80359459
GWAS Ctlg	rs80359459

Max Magnitude

6

rs80359459, also known as 690delAA, c.462_463delAA and p.Gln154_Arg155=fs, is a variant in the BRCA2 gene considered pathogenic for breast cancer in ClinVar.

ClinVar
Risk	rs80359459(-;-)
Alt	rs80359459(-;-)
Reference	Rs80359459(AA;AA)
Significance	Pathogenic
Disease	Familial cancer of breast Breast-ovarian cancer Hereditary cancer-predisposing syndrome
Variation	info
Gene	BRCA2
CLNDBN	Familial cancer of breast Breast-ovarian cancer, familial 2 Hereditary cancer-predisposing syndrome
Reversed	0
HGVS	NC_000013.10:g.32900274_32900275delAA
CLNSRC	Breast Cancer Information Core (BRCA2)
CLNACC	RCV000044454.2, RCV000077331.5, RCV000219738.1,