rs80359505

plus

Geno	Mag	Summary
(-;TT)	6	BRCA2 variant considered pathogenic for breast cancer
(TT;TT)	0	common in clinvar

Make rs80359505(-;-)

Reference

GRCh38 38.1/141

Chromosome

13

Position

32339658

Gene

BRCA2

is a	snp
is	mentioned by
dbSNP	rs80359505
dbSNP (classic)	rs80359505
ClinGen	rs80359505
ebi	rs80359505
HLI	rs80359505
Exac	rs80359505
Gnomad	rs80359505
Varsome	rs80359505
LitVar	rs80359505
Map	rs80359505
PheGenI	rs80359505
Biobank	rs80359505
1000 genomes	rs80359505
hgdp	rs80359505
ensembl	rs80359505
geneview	rs80359505
scholar	rs80359505
google	rs80359505
pharmgkb	rs80359505
gwascentral	rs80359505
openSNP	rs80359505
23andMe	rs80359505
SNPshot	rs80359505
SNPdbe	rs80359505
MSV3d	rs80359505
GWAS Ctlg	rs80359505

Max Magnitude

6

rs80359505, also known as 5531delTT, c. 5303_5304delTT and p.Leu1768Argfs, is a variant in the BRCA2 gene considered pathogenic for breast cancer in ClinVar.

ClinVar
Risk	rs80359505(-;-)
Alt	rs80359505(-;-)
Reference	Rs80359505(TT;TT)
Significance	Pathogenic
Disease	Breast-ovarian cancer Hereditary breast and ovarian cancer syndrome Hereditary cancer-predisposing syndrome not provided
Variation	info
Gene	BRCA2
CLNDBN	Breast-ovarian cancer, familial 2 Hereditary breast and ovarian cancer syndrome Hereditary cancer-predisposing syndrome not provided
Reversed	0
HGVS	NC_000013.10:g.32913795_32913796delTT
CLNSRC	Breast Cancer Information Core (BRCA2)
CLNACC	RCV000031538.7, RCV000074536.6, RCV000162923.2, RCV000235139.1,