rs80359541

plus

Geno	Mag	Summary
(-;C)	6	Likely miscall in Ancestry v2c data; otherwise, BRCA2 variant considered pathogenic for breast cancer
(C;C)	0	common in clinvar

Make rs80359541(-;-)

Reference

GRCh38 38.1/141

Chromosome

13

Position

32340183

Gene

BRCA2

is a	snp
is	mentioned by
dbSNP	rs80359541
dbSNP (classic)	rs80359541
ClinGen	rs80359541
ebi	rs80359541
HLI	rs80359541
Exac	rs80359541
Gnomad	rs80359541
Varsome	rs80359541
LitVar	rs80359541
Map	rs80359541
PheGenI	rs80359541
Biobank	rs80359541
1000 genomes	rs80359541
hgdp	rs80359541
ensembl	rs80359541
geneview	rs80359541
scholar	rs80359541
google	rs80359541
pharmgkb	rs80359541
gwascentral	rs80359541
openSNP	rs80359541
23andMe	rs80359541
SNPshot	rs80359541
SNPdbe	rs80359541
MSV3d	rs80359541
GWAS Ctlg	rs80359541

Max Magnitude

6

rs80359541, also known as 6056delC, c.5828_5828delC and p.Ser1943Leufs, is a variant in the BRCA2 gene considered pathogenic for breast cancer in ClinVar.

ClinVar
Risk	rs80359541(-;-)
Alt	rs80359541(-;-)
Reference	Rs80359541(C;C)
Significance	Pathogenic
Disease	Breast-ovarian cancer not provided Hereditary cancer-predisposing syndrome Hereditary breast and ovarian cancer syndrome
Variation	info
Gene	BRCA2
CLNDBN	Breast-ovarian cancer, familial 2 not provided Hereditary cancer-predisposing syndrome Hereditary breast and ovarian cancer syndrome
Reversed	0
HGVS	NC_000013.10:g.32914320delC
CLNSRC	Breast Cancer Information Core (BRCA2)
CLNACC	RCV000031580.7, RCV000044766.6, RCV000131318.3, RCV000195355.2,