rs80359627

plus

Geno	Mag	Summary
(-;TCTTA)	6	BRCA2 variant considered pathogenic for breast cancer
(CTTAT;CTTAT)	0	common in clinvar
(TCTTA;TCTTA)	0	common in clinvar

Make rs80359627(-;-)

Reference

GRCh38 38.1/141

Chromosome

13

Position

32341188

Gene

BRCA2

is a	snp
is	mentioned by
dbSNP	rs80359627
dbSNP (classic)	rs80359627
ClinGen	rs80359627
ebi	rs80359627
HLI	rs80359627
Exac	rs80359627
Gnomad	rs80359627
Varsome	rs80359627
LitVar	rs80359627
Map	rs80359627
PheGenI	rs80359627
Biobank	rs80359627
1000 genomes	rs80359627
hgdp	rs80359627
ensembl	rs80359627
geneview	rs80359627
scholar	rs80359627
google	rs80359627
pharmgkb	rs80359627
gwascentral	rs80359627
openSNP	rs80359627
23andMe	rs80359627
SNPshot	rs80359627
SNPdbe	rs80359627
MSV3d	rs80359627
GWAS Ctlg	rs80359627

Status

Merged into rs80359626

Max Magnitude

6

rs80359627, also known as 7061del5, c.6833_6837delTCTTA and p.Ile2278_Leu2279?fs, is a variant in the BRCA2 gene considered pathogenic for breast cancer in ClinVar.

ClinVar
Risk
Alt
Reference	Rs80359627(CTTAT;CTTAT)
Significance	Pathogenic
Disease	Familial cancer of breast Breast-ovarian cancer Hereditary cancer-predisposing syndrome
Variation	info
Gene	BRCA2
CLNDBN	Familial cancer of breast Breast-ovarian cancer, familial 2 Hereditary cancer-predisposing syndrome
Reversed	0
HGVS	NC_000013.10:g.32915325_32915329delTCTTA
CLNSRC	Breast Cancer Information Core (BRCA2)
CLNACC	RCV000045068.2, RCV000113656.4, RCV000162934.2,