rs80359646

plus

Geno	Mag	Summary
(-;A)	6	BRCA2 variant considered pathogenic for breast cancer
(A;A)	0	common in clinvar

Make rs80359646(-;-)

Reference

GRCh38 38.1/141

Chromosome

13

Position

32355213

Gene

BRCA2

is a	snp
is	mentioned by
dbSNP	rs80359646
dbSNP (classic)	rs80359646
ClinGen	rs80359646
ebi	rs80359646
HLI	rs80359646
Exac	rs80359646
Gnomad	rs80359646
Varsome	rs80359646
LitVar	rs80359646
Map	rs80359646
PheGenI	rs80359646
Biobank	rs80359646
1000 genomes	rs80359646
hgdp	rs80359646
ensembl	rs80359646
geneview	rs80359646
scholar	rs80359646
google	rs80359646
pharmgkb	rs80359646
gwascentral	rs80359646
openSNP	rs80359646
23andMe	rs80359646
SNPshot	rs80359646
SNPdbe	rs80359646
MSV3d	rs80359646
GWAS Ctlg	rs80359646

Max Magnitude

6

rs80359646, also known as 7588delA, c.7360_7360delA and p.Ile2454Phefs, is a variant in the BRCA2 gene considered pathogenic for breast cancer in ClinVar.

ClinVar
Risk	rs80359646(-;-)
Alt	rs80359646(-;-)
Reference	Rs80359646(A;A)
Significance	Pathogenic
Disease	Hereditary breast and ovarian cancer syndrome Breast-ovarian cancer not provided
Variation	info
Gene	BRCA2
CLNDBN	Hereditary breast and ovarian cancer syndrome Breast-ovarian cancer, familial 2 not provided
Reversed	0
HGVS	NC_000013.10:g.32929350delA
CLNSRC	Breast Cancer Information Core (BRCA2)
CLNACC	RCV000045191.3, RCV000113747.3, RCV000484324.1,