rs80359659

plus

Geno	Mag	Summary
(-;ACAG)	6	BRCA2 variant considered pathogenic for breast cancer
(ACAG;ACAG)	0	common in clinvar
(GACA;GACA)	0	common in clinvar

Make rs80359659(-;-)

Reference

GRCh38 38.1/141

Chromosome

13

Position

32330992

Gene

BRCA2

is a	snp
is	mentioned by
dbSNP	rs80359659
dbSNP (classic)	rs80359659
ClinGen	rs80359659
ebi	rs80359659
HLI	rs80359659
Exac	rs80359659
Gnomad	rs80359659
Varsome	rs80359659
LitVar	rs80359659
Map	rs80359659
PheGenI	rs80359659
Biobank	rs80359659
1000 genomes	rs80359659
hgdp	rs80359659
ensembl	rs80359659
geneview	rs80359659
scholar	rs80359659
google	rs80359659
pharmgkb	rs80359659
gwascentral	rs80359659
openSNP	rs80359659
23andMe	rs80359659
SNPshot	rs80359659
SNPdbe	rs80359659
MSV3d	rs80359659
GWAS Ctlg	rs80359659

Max Magnitude

6

rs80359659, also known as 983del4, c.755_758delACAG and p.Asp252_Ser253?fs, is a variant in the BRCA2 gene considered pathogenic for breast cancer in ClinVar.

ClinVar
Risk	rs80359659(-;-)
Alt	rs80359659(-;-)
Reference	Rs80359659(GACA;GACA)
Significance	Pathogenic
Disease	Breast-ovarian cancer not provided Hereditary cancer-predisposing syndrome Hereditary breast and ovarian cancer syndrome
Variation	info
Gene	BRCA2
CLNDBN	Breast-ovarian cancer, familial 2 not provided Hereditary cancer-predisposing syndrome Hereditary breast and ovarian cancer syndrome
Reversed	0
HGVS	NC_000013.10:g.32905129_32905132delACAG
CLNSRC	Breast Cancer Information Core (BRCA2)
CLNACC	RCV000031685.9, RCV000045245.7, RCV000162899.3, RCV000167860.3,