rs80359706

plus

Geno	Mag	Summary
(-;-)	0	common in clinvar
(-;T)	6	BRCA2 variant considered pathogenic for breast cancer

Make rs80359706(T;T)

Reference

GRCh38 38.1/141

Chromosome

13

Position

32363524

Gene

BRCA2

is a	snp
is	mentioned by
dbSNP	rs80359706
dbSNP (classic)	rs80359706
ClinGen	rs80359706
ebi	rs80359706
HLI	rs80359706
Exac	rs80359706
Gnomad	rs80359706
Varsome	rs80359706
LitVar	rs80359706
Map	rs80359706
PheGenI	rs80359706
Biobank	rs80359706
1000 genomes	rs80359706
hgdp	rs80359706
ensembl	rs80359706
geneview	rs80359706
scholar	rs80359706
google	rs80359706
pharmgkb	rs80359706
gwascentral	rs80359706
openSNP	rs80359706
23andMe	rs80359706
SNPshot	rs80359706
SNPdbe	rs80359706
MSV3d	rs80359706
GWAS Ctlg	rs80359706

Max Magnitude

6

rs80359706, also known as 8550insT, c.8322_8323insT and p.Leu2774_Met2775?fs, is a variant in the BRCA2 gene considered pathogenic for breast cancer in ClinVar.

ClinVar
Risk	rs80359706(T;T)
Alt	rs80359706(T;T)
Reference	Rs80359706(-;-)
Significance	Pathogenic
Disease	Breast-ovarian cancer Familial cancer of breast Hereditary cancer-predisposing syndrome Neoplasm of breast not provided
Variation	info
Gene	BRCA2
CLNDBN	Breast-ovarian cancer, familial 2 Familial cancer of breast Hereditary cancer-predisposing syndrome Neoplasm of breast not provided
Reversed	0
HGVS	NC_000013.10:g.32937661dupT
CLNSRC	Breast Cancer Information Core (BRCA2)
CLNACC	RCV000031736.6, RCV000045472.2, RCV000220249.1, RCV000240726.1, RCV000377823.2,