rs80359727

plus

Geno	Mag	Summary
(-;-)	0	common in clinvar
(-;TTAC)	6	BRCA2 variant considered pathogenic for breast cancer

Make rs80359727(TTAC;TTAC)

Reference

GRCh38 38.1/142

Chromosome

13

Position

32376785

Gene

BRCA2

is a	snp
is	mentioned by
dbSNP	rs80359727
dbSNP (classic)	rs80359727
ClinGen	rs80359727
ebi	rs80359727
HLI	rs80359727
Exac	rs80359727
Gnomad	rs80359727
Varsome	rs80359727
LitVar	rs80359727
Map	rs80359727
PheGenI	rs80359727
Biobank	rs80359727
1000 genomes	rs80359727
hgdp	rs80359727
ensembl	rs80359727
geneview	rs80359727
scholar	rs80359727
google	rs80359727
pharmgkb	rs80359727
gwascentral	rs80359727
openSNP	rs80359727
23andMe	rs80359727
SNPshot	rs80359727
SNPdbe	rs80359727
MSV3d	rs80359727
GWAS Ctlg	rs80359727

Max Magnitude

6

rs80359727, also known as 8976ins4, c.8748_8749insTTAC and p.Tyr2916_Leu2917?fs, is a variant in the BRCA2 gene considered pathogenic for breast cancer in ClinVar.

ClinVar
Risk	rs80359727(CTTA;CTTA)
Alt	rs80359727(CTTA;CTTA)
Reference	Rs80359727(-;-)
Significance	Pathogenic
Disease	Breast-ovarian cancer Hereditary breast and ovarian cancer syndrome
Variation	info
Gene	BRCA2
CLNDBN	Breast-ovarian cancer, familial 2 Hereditary breast and ovarian cancer syndrome
Reversed	0
HGVS	NC_000013.10:g.32950919_32950922dupTTAC
CLNSRC	Breast Cancer Information Core (BRCA2)
CLNACC	RCV000113991.2, RCV000228171.1,