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rs8040868

From SNPedia

Orientationplus
Stabilizedplus
Make rs8040868(C;C)
Make rs8040868(C;T)
Make rs8040868(T;T)
ReferenceGRCh38 38.1/141
Chromosome15
Position78618839
GeneCHRNA3
is asnp
is mentioned by
dbSNPrs8040868
ebirs8040868
HLIrs8040868
Exacrs8040868
Varsomers8040868
Maprs8040868
PheGenIrs8040868
hapmaprs8040868
1000 genomesrs8040868
hgdprs8040868
ensemblrs8040868
gopubmedrs8040868
geneviewrs8040868
scholarrs8040868
googlers8040868
pharmgkbrs8040868
gwascentralrs8040868
openSNPrs8040868
23andMers8040868
23andMe allrs8040868
SNP Nexus

SNPshotrs8040868
SNPdbers8040868
MSV3drs8040868
GWAS Ctlgrs8040868
GMAF0.3774
Max Magnitude
? (C;C) (C;T) (T;T) 28
[PMID 19859904OA-icon.png] Association and interaction analysis of variants in CHRNA5/CHRNA3/CHRNB4 gene cluster with nicotine dependence in African and European Americans


[PMID 22280835OA-icon.png] New associations of the genetic polymorphisms in nicotinic receptor genes with the risk of lung cancer


[PMID 18163978OA-icon.png] The CHRNA5/A3/B4 gene cluster variability as an important determinant of early alcohol and tobacco initiation in young adults.


[PMID 18165968OA-icon.png] Identification of pharmacogenetic markers in smoking cessation therapy.


[PMID 19330903OA-icon.png] Gene by smoking interaction in hypertension: identification of a major quantitative trait locus on chromosome 15q for systolic blood pressure in Mexican-Americans.


[PMID 19443489OA-icon.png] Risk for nicotine dependence and lung cancer is conferred by mRNA expression levels and amino acid change in CHRNA5.


[PMID 20808433OA-icon.png] Associations of variants in CHRNA5/A3/B4 gene cluster with smoking behaviors in a Korean population.


[PMID 22042234OA-icon.png] Externalizing behaviors are associated with SNPs in the CHRNA5/CHRNA3/CHRNB4 gene cluster.


[PMID 23196875OA-icon.png] Variants in the 15q25 gene cluster are associated with risk for schizophrenia and bipolar disorder

GWAS snp
PMID [PMID 23284291OA-icon.png]
Trait Pulmonary function (interaction)
Title Genome-wide joint meta-analysis of SNP and SNP-by-smoking interaction identifies novel loci for pulmonary function.
Risk Allele T
P-val 9E-8
Odds Ratio NR NR


[PMID 22945651OA-icon.png] Epigenetic screen identifies genotype-specific promoter DNA methylation and oncogenic potential of CHRNB4.

GWAS snp
PMID [PMID 23251661OA-icon.png]
Trait Obesity-related traits
Title Novel genetic loci identified for the pathophysiology of childhood obesity in the Hispanic population.
Risk Allele G
P-val 6E-8
Odds Ratio .05 [NR] kcal/d increase


[PMID 25399010] Association between polymorphisms in CHRNA3 and PHACTR2 gene and environment and NSCLC risk in Chinese population