|?|| (C;C) (C;T) (T;T) ||28|
] Association and interaction analysis of variants in CHRNA5/CHRNA3/CHRNB4 gene cluster with nicotine dependence in African and European Americans
[PMID 22280835] New associations of the genetic polymorphisms in nicotinic receptor genes with the risk of lung cancer
[PMID 18163978] The CHRNA5/A3/B4 gene cluster variability as an important determinant of early alcohol and tobacco initiation in young adults.
[PMID 18165968] Identification of pharmacogenetic markers in smoking cessation therapy.
[PMID 19330903] Gene by smoking interaction in hypertension: identification of a major quantitative trait locus on chromosome 15q for systolic blood pressure in Mexican-Americans.
[PMID 19443489] Risk for nicotine dependence and lung cancer is conferred by mRNA expression levels and amino acid change in CHRNA5.
[PMID 20808433] Associations of variants in CHRNA5/A3/B4 gene cluster with smoking behaviors in a Korean population.
[PMID 22042234] Externalizing behaviors are associated with SNPs in the CHRNA5/CHRNA3/CHRNB4 gene cluster.
[PMID 23196875] Variants in the 15q25 gene cluster are associated with risk for schizophrenia and bipolar disorder
[PMID 22945651] Epigenetic screen identifies genotype-specific promoter DNA methylation and oncogenic potential of CHRNB4.
|| [PMID 23251661]
|| Obesity-related traits
|| Novel genetic loci identified for the pathophysiology of childhood obesity in the Hispanic population.
| Risk Allele
| Odds Ratio
|| .05 [NR] kcal/d increase
[PMID 25399010] Association between polymorphisms in CHRNA3 and PHACTR2 gene and environment and NSCLC risk in Chinese population