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rs8042374

From SNPedia

May affect lung cancer risk
Orientationplus
Stabilizedplus
Make rs8042374(A;A)
Make rs8042374(A;G)
Make rs8042374(G;G)
ReferenceGRCh38 38.1/141
Chromosome15
Position78615690
GeneCHRNA3
is asnp
is mentioned by
dbSNPrs8042374
ebirs8042374
HLIrs8042374
Exacrs8042374
Varsomers8042374
Maprs8042374
PheGenIrs8042374
hapmaprs8042374
1000 genomesrs8042374
hgdprs8042374
ensemblrs8042374
gopubmedrs8042374
geneviewrs8042374
scholarrs8042374
googlers8042374
pharmgkbrs8042374
gwascentralrs8042374
openSNPrs8042374
23andMers8042374
23andMe allrs8042374
SNP Nexus

SNPshotrs8042374
SNPdbers8042374
MSV3drs8042374
GWAS Ctlgrs8042374
GMAF0.4385
Max Magnitude
? (A;A) (A;G) (G;G) 28
[PMID 18978787OA-icon.png] lung cancer rs8042374 P = 7.75 x 10(-12)
OMIM612052
DescLUNG CANCER SUSCEPTIBILITY 2; LNCR2
Variant
Relatedalso
[PMID 18519524OA-icon.png] Variants in nicotinic receptors and risk for nicotine dependence.


[PMID 19654303OA-icon.png] Deciphering the impact of common genetic variation on lung cancer risk: a genome-wide association study.


[PMID 19706762OA-icon.png] The CHRNA5-CHRNA3-CHRNB4 nicotinic receptor subunit gene cluster affects risk for nicotine dependence in African-Americans and in European-Americans.


[PMID 19955392] Role of 5p15.33 (TERT-CLPTM1L), 6p21.33 and 15q25.1 (CHRNA5-CHRNA3) variation and lung cancer risk in never-smokers.


GET Evidence
rs8042374
aa_change
aa_change_short
impact pathogenic
qualified_impact Insufficiently evaluated pathogenic
overall_frequency 0.351562
summary