|?|| (A;A) (A;G) (G;G) ||28|
has been reported in a large study to be associated with Crohn's disease
The risk allele (oriented to the dbSNP entry) is (G); the odds ratio associated with heterozygotes is 1.47 (CI 1.25-1.73), and for homozygotes, 1.28 (CI 0.56-2.88). [PMID 17554300]
|| [PMID 21658281]
|| GWAS for discovery and replication of genetic loci associated with sudden cardiac arrest in patients with coronary artery disease.
| Risk Allele
| Odds Ratio
|| 2.0100 [1.50-2.70]
[PMID 20018022] Replication of recently identified associated single-nucleotide polymorphisms from six autoimmune diseases in Genetic Analysis Workshop 16 rheumatoid arthritis data.