|| decreased baroreflex sensitivity, heart rate variability, and in women, hypertension
rs841, also known as C+243T or C59038T, is a SNP in the 3' UTR of the GTP cyclohydrolase 1 GCH1 gene on chromosome 14.
For the associations reported for rs841(T;T), see [PMID 17717598].
|?|| (C;C) (C;T) (T;T) ||28|
] Exploring epistatic relationships of NO biosynthesis pathway genes in susceptibility to CHD
[PMID 21963893] Polymorphisms of genes in nitric oxide-forming pathway associated with ischemic stroke in Chinese Han population
[PMID 17343757] Lack of influence of GTP cyclohydrolase gene (GCH1) variations on pain sensitivity in humans.
[PMID 19775452] Do genetic predictors of pain sensitivity associate with persistent widespread pain?
[PMID 21896313] Functional polymorphism of the GTP cyclohydrolase 1 gene affects the personality trait of novelty seeking in healthy subjects.
[PMID 22770721] GTP cyclohydrolase 1 gene haplotypes as predictors of SSRI response in Japanese patients with major depressive disorder
[PMID 23246742] Association of monoamine-synthesizing genes with the depression tendency and personality in chronic fatigue syndrome patients.
[PMID 23322459] Association of guanosine triphosphate cyclohydrolase 1 gene polymorphisms with fibromyalgia syndrome in a Korean population.