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rs841

From SNPedia

Orientationminus
Stabilizedminus
Geno Mag Summary
(T;T) 2 decreased baroreflex sensitivity, heart rate variability, and in women, hypertension
Make rs841(C;C)
Make rs841(C;T)
ReferenceGRCh38 38.1/141
Chromosome14
Position54843774
GeneGCH1
is asnp
is mentioned by
dbSNPrs841
ebirs841
HLIrs841
Exacrs841
Varsomers841
Maprs841
PheGenIrs841
hapmaprs841
1000 genomesrs841
hgdprs841
ensemblrs841
gopubmedrs841
geneviewrs841
scholarrs841
googlers841
pharmgkbrs841
gwascentralrs841
openSNPrs841
23andMers841
23andMe allrs841
SNP Nexus

SNPshotrs841
SNPdbers841
MSV3drs841
GWAS Ctlgrs841
GMAF0.2672
Max Magnitude2

rs841, also known as C+243T or C59038T, is a SNP in the 3' UTR of the GTP cyclohydrolase 1 GCH1 gene on chromosome 14.

For the associations reported for rs841(T;T), see [PMID 17717598OA-icon.png].

? (C;C) (C;T) (T;T) 28
[PMID 20581851OA-icon.png] Exploring epistatic relationships of NO biosynthesis pathway genes in susceptibility to CHD


[PMID 21963893OA-icon.png] Polymorphisms of genes in nitric oxide-forming pathway associated with ischemic stroke in Chinese Han population


[PMID 17343757OA-icon.png] Lack of influence of GTP cyclohydrolase gene (GCH1) variations on pain sensitivity in humans.


[PMID 19775452OA-icon.png] Do genetic predictors of pain sensitivity associate with persistent widespread pain?


[PMID 21896313] Functional polymorphism of the GTP cyclohydrolase 1 gene affects the personality trait of novelty seeking in healthy subjects.


[PMID 22770721] GTP cyclohydrolase 1 gene haplotypes as predictors of SSRI response in Japanese patients with major depressive disorder


[PMID 23246742] Association of monoamine-synthesizing genes with the depression tendency and personality in chronic fatigue syndrome patients.


[PMID 23322459] Association of guanosine triphosphate cyclohydrolase 1 gene polymorphisms with fibromyalgia syndrome in a Korean population.