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rs858518

From SNPedia

Orientationminus
Stabilizedplus
Make rs858518(C;C)
Make rs858518(C;T)
Make rs858518(T;T)
ReferenceGRCh38 38.1/142
Chromosome17
Position7629707
GeneSAT2, SHBG
is asnp
is mentioned by
dbSNPrs858518
ebirs858518
HLIrs858518
Exacrs858518
Varsomers858518
Maprs858518
PheGenIrs858518
hapmaprs858518
1000 genomesrs858518
hgdprs858518
ensemblrs858518
gopubmedrs858518
geneviewrs858518
scholarrs858518
googlers858518
pharmgkbrs858518
gwascentralrs858518
openSNPrs858518
23andMers858518
23andMe allrs858518
SNP Nexus

SNPshotrs858518
SNPdbers858518
MSV3drs858518
GWAS Ctlgrs858518
GMAF0.4256
Max Magnitude
is a SNP in the sex-hormone binding globulin (SHBG) gene. SHBG binds steroid hormones, mostly testosterone and estradiol, rendering them biologically unavailable.

[PMID 19064566OA-icon.png] Ten SNPs within or close to the SHBG gene were significantly associated with SHBG levels as was the (TAAAA)(n) polymorphism. The best-fitting combination of rs6259, rs858521, and rs727428 and body mass index, waist, hip, age, and smoking status accounted for 24% of the variance in SHBG levels (natural logarithm transformed).