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rs9271366

From SNPedia

Orientationplus
Stabilizedplus
Make rs9271366(A;A)
Make rs9271366(A;G)
Make rs9271366(G;G)
ReferenceGRCh38 38.1/141
Chromosome6
Position32619077
is asnp
is mentioned by
dbSNPrs9271366
ebirs9271366
HLIrs9271366
Exacrs9271366
Varsomers9271366
Maprs9271366
PheGenIrs9271366
hapmaprs9271366
1000 genomesrs9271366
hgdprs9271366
ensemblrs9271366
gopubmedrs9271366
geneviewrs9271366
scholarrs9271366
googlers9271366
pharmgkbrs9271366
gwascentralrs9271366
openSNPrs9271366
23andMers9271366
23andMe allrs9271366
SNP Nexus

SNPshotrs9271366
SNPdbers9271366
MSV3drs9271366
GWAS Ctlgrs9271366
GMAF0.1382
Max Magnitude
? (A;A) (A;G) (G;G) 28
GWAS snp
PMID [PMID 19525955]
Trait Multiple sclerosis
Title Genome-wide association study identifies new multiple sclerosis susceptibility loci on chromosomes 12 and 20
Risk Allele G
P-val 0
Odds Ratio 2.78 [NR]
GWAS snp
PMID [PMID 20598377]
Trait Multiple sclerosis
Title Evidence for VAV2 and ZNF433 as susceptibility genes for multiple sclerosis
Risk Allele G
P-val 4E-17
Odds Ratio 2.62 [2.09-3.28]
GWAS snp
PMID [PMID 20694011]
Trait
Title Association of IFIH1 and other autoimmunity risk alleles with selective IgA deficiency
Risk Allele
P-val 3E-33
Odds Ratio 7.69 [5.26-11.11]


[PMID 21695597OA-icon.png] MHC region and risk of systemic lupus erythematosus in African American women

GWAS snp
PMID [PMID 21699788]
Trait
Title HLA-Cw*1202-B*5201-DRB1*1502 Haplotype Increases Risk for Ulcerative Colitis But Reduces Risk for Crohn's Disease.
Risk Allele C
P-val 2E-70
Odds Ratio 4.4400 [3.74-5.27]

[PMID 18462017OA-icon.png] Mapping the genetic architecture of gene expression in human liver.

[PMID 19143821OA-icon.png] Association of MHC SNP genotype with susceptibility to type 1 diabetes: a modified survival approach.

[PMID 19838195OA-icon.png] A large-scale replication study identifies TNIP1, PRDM1, JAZF1, UHRF1BP1 and IL10 as risk loci for systemic lupus erythematosus.

[PMID 20045101OA-icon.png] Quantitative trait loci for CD4:CD8 lymphocyte ratio are associated with risk of type 1 diabetes and HIV-1 immune control.

[PMID 20169177OA-icon.png] Genome-wide association study in Asian populations identifies variants in ETS1 and WDFY4 associated with systemic lupus erythematosus.

[PMID 20405052OA-icon.png] The effect of single nucleotide polymorphisms from genome wide association studies in multiple sclerosis on gene expression.

[PMID 20546594OA-icon.png] An application of Random Forests to a genome-wide association dataset: methodological considerations & new findings.

[PMID 21408207OA-icon.png] Differential genetic associations for systemic lupus erythematosus based on anti-dsDNA autoantibody production.


GET Evidence
rs9271366
aa_change
aa_change_short
impact pathogenic
qualified_impact Insufficiently evaluated pathogenic
overall_frequency 0.860656
summary



[PMID 23257407] HLA variants rs9271366 and rs9275328 are associated with systemic lupus erythematosus susceptibility in Malays and Chinese

GWAS snp
PMID [PMID 23511034]
Trait Ulcerative colitis
Title Genome-wide association study of ulcerative colitis in Koreans suggests extensive overlapping of genetic susceptibility with Caucasians.
Risk Allele G
P-val 1E-18
Odds Ratio 2.10 [1.78-2.48]


[PMID 24458077OA-icon.png] Association of Systemic Lupus Erythematosus Susceptibility Genes with IgA Nephropathy in a Chinese Cohort

GWAS snp
PMID [PMID 23850713]
Trait Crohn's disease
Title Genome-wide association study of Crohn's disease in Koreans revealed three new susceptibility loci and common attributes of genetic susceptibility across ethnic populations.
Risk Allele A
P-val 5E-12
Odds Ratio 1.66 [1.44-1.92]