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rs9273363

From SNPedia

23andMe's Type 1 Diabetes SNP
Orientationplus
Stabilizedplus
Geno Mag Summary
(A;A) 2 Higher risk of Type 1 Diabetes.
(A;C) 2 Lower 0.87x risk of Type 1 Diabetes.
(C;C) 2.1 Much lower 0.15x risk of Type 1 Diabetes.
ReferenceGRCh38 38.1/141
Chromosome6
Position32658495
GeneHLA-DQB1
is asnp
is mentioned by
dbSNPrs9273363
ebirs9273363
HLIrs9273363
Exacrs9273363
Varsomers9273363
Maprs9273363
PheGenIrs9273363
hapmaprs9273363
1000 genomesrs9273363
hgdprs9273363
ensemblrs9273363
gopubmedrs9273363
geneviewrs9273363
scholarrs9273363
googlers9273363
pharmgkbrs9273363
gwascentralrs9273363
openSNPrs9273363
23andMers9273363
23andMe allrs9273363
SNP Nexus

SNPshotrs9273363
SNPdbers9273363
MSV3drs9273363
GWAS Ctlgrs9273363
GMAF0.2576
Max Magnitude2.1
? (A;A) (A;C) (C;C) 28

This is one of the SNPs that 23andMe uses for Type 1 diabetes. According to 23andMe, this SNP changes your risk of Type 1 Diabetes. That is an autoimmune disease where your immune system attacks your own body's insulin producing cells in the pancreas, preventing your blood sugar from being able to enter cells that need energy. This has been verified for white people. 23andMe originally wanted to use rs9272346 instead, but it was deemed unreliable.

GWAS snp
PMID [PMID 23770605OA-icon.png]
Trait Chronic lymphocytic leukemia
Title Genome-wide association study identifies multiple risk loci for chronic lymphocytic leukemia.
Risk Allele A
P-val 2E-10
Odds Ratio 1.24 [NR]


[PMID 19956648OA-icon.png] Pathway analysis of GWAS provides new insights into genetic susceptibility to 3 inflammatory diseases.


[PMID 20018019OA-icon.png] Two-stage joint selection method to identify candidate markers from genome-wide association studies.