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rs9277378

From SNPedia

Orientationplus
Stabilizedplus
Make rs9277378(A;A)
Make rs9277378(A;G)
Make rs9277378(G;G)
ReferenceGRCh38 38.1/141
Chromosome6
Position33082502
GeneHLA-DPA1, HLA-DPB1
is asnp
is mentioned by
dbSNPrs9277378
ebirs9277378
HLIrs9277378
Exacrs9277378
Varsomers9277378
Maprs9277378
PheGenIrs9277378
hapmaprs9277378
1000 genomesrs9277378
hgdprs9277378
ensemblrs9277378
gopubmedrs9277378
geneviewrs9277378
scholarrs9277378
googlers9277378
pharmgkbrs9277378
gwascentralrs9277378
openSNPrs9277378
23andMers9277378
23andMe allrs9277378
SNP Nexus

SNPshotrs9277378
SNPdbers9277378
MSV3drs9277378
GWAS Ctlgrs9277378
GMAF0.4642
Max Magnitude

Located in the HLA-DPB1 gene, the rs9277378(A) allele is reported in a study of ~800 Chinese patients as roughly doubling risk for the nasal type of extranodal natural killer T-cell lymphoma (NKTCL; CI:1.6-2.1, p=4·21 × 10e−19). This rare, aggressive malignancy occurs predominantly in Asian and Latin American populations.[PMID 27470079]

? (A;A) (A;G) (G;G) 28
[PMID 24465836OA-icon.png] Genetic association of human leukocyte antigens with chronicity or resolution of hepatitis B infection in thai population


[PMID 19116921OA-icon.png] Different patterns of associations with anti-citrullinated protein antibody-positive and anti-citrullinated protein antibody-negative rheumatoid arthritis in the extended major histocompatibility complex region.


[PMID 23449268] HLA-DP and IL28B polymorphisms: influence of host genome on hepatitis B surface antigen seroclearance in chronic hepatitis B.


[PMID 27595289] Novel HLA-DP region susceptibility loci associated with severe acute GvHD.