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rs9288516

From SNPedia

Orientationplus
Stabilizedplus
Geno Mag Summary
(A;A) 2 2x higher risk for hepatocellular cancer
(A;T) 2 2x higher risk for hepatocellular cancer
(T;T) 0 common in complete genomics
ReferenceGRCh38 38.1/141
Chromosome2
Position216188541
GeneXRCC5
is asnp
is mentioned by
dbSNPrs9288516
ebirs9288516
HLIrs9288516
Exacrs9288516
Varsomers9288516
Maprs9288516
PheGenIrs9288516
hapmaprs9288516
1000 genomesrs9288516
hgdprs9288516
ensemblrs9288516
gopubmedrs9288516
geneviewrs9288516
scholarrs9288516
googlers9288516
pharmgkbrs9288516
gwascentralrs9288516
openSNPrs9288516
23andMers9288516
23andMe allrs9288516
SNP Nexus

SNPshotrs9288516
SNPdbers9288516
MSV3drs9288516
GWAS Ctlgrs9288516
GMAF0.1809
Max Magnitude2
? (A;A) (A;T) (T;T) 28
rs9288516 is a SNP in the XRCC5 gene.

A study of ~700 Chinese patients with hepatocellular carcinoma (HCC) compared to controls indicated an increased risk for rs9288516(A) carriers (odds ratio 2.02, CI: 1.42-2.86, TA+AA versus TT) even after Bonferroni correction (P(corrected) = 0.002). The effect was more significant in HBsAg infected subjects than non-infected subjects.[PMID 21304054] [PMID 17389609] Tagging SNPs in non-homologous end-joining pathway genes and risk of glioma.


[PMID 19318434OA-icon.png] Associations between polymorphisms in DNA repair genes and glioblastoma.


[PMID 27852033] The relationship between polymorphisms of XRCC5 genes with astrocytoma prognosis in the Han Chinese population.