Have questions? Visit https://www.reddit.com/r/SNPedia

rs9292777

From SNPedia

Orientationplus
Stabilizedplus
Make rs9292777(C;C)
Make rs9292777(C;T)
Make rs9292777(T;T)
ReferenceGRCh38 38.1/141
Chromosome5
Position40437846
is asnp
is mentioned by
dbSNPrs9292777
ebirs9292777
HLIrs9292777
Exacrs9292777
Varsomers9292777
Maprs9292777
PheGenIrs9292777
hapmaprs9292777
1000 genomesrs9292777
hgdprs9292777
ensemblrs9292777
gopubmedrs9292777
geneviewrs9292777
scholarrs9292777
googlers9292777
pharmgkbrs9292777
gwascentralrs9292777
openSNPrs9292777
23andMers9292777
23andMe allrs9292777
SNP Nexus

SNPshotrs9292777
SNPdbers9292777
MSV3drs9292777
GWAS Ctlgrs9292777
GMAF0.4738
Max Magnitude
? (C;C) (C;T) (T;T) 28
Rs9292777
PubMed [PMID 17447842OA-icon.png]
Affy Probeset SNP_A-2211129
Affy Orientation same
On GW 5.0 1
Alleles A/B C/T
Ancestral C
Population EU
Allele T
Case Freq. 0.68
Control Freq. 0.59
Odds Ratio Het
Odds Ratio Hom
Odds Ratio All 1.46
Disease Crohn's disease (CD)


rs9292777 is in linkage disequilibrium with a polymorphism that increases susceptibility to Crohn's disease 1.46 times for carriers of the T allele [PMID 17447842OA-icon.png]

GWAS snp
PMID [PMID 17554261OA-icon.png]
Trait Crohn's disease
Title Sequence variants in the autophagy gene IRGM and multiple other replicating loci contribute to Crohn's disease susceptibility
Risk Allele
P-val 2.9999999999999998E-18
Odds Ratio 1.34 [1.20-1.50]


[PMID 19953089] Differences in genetic background between active smokers, passive smokers, and non-smokers with Crohn's disease

GWAS snp
PMID [PMID 22570697OA-icon.png]
Trait
Title Genome-wide association study of multiple sclerosis confirms a novel locus at 5p13.1.
Risk Allele T
P-val 1E-9
Odds Ratio 1.1900 None
GWAS snp
PMID [PMID 22412388OA-icon.png]
Trait
Title A genome-wide scan of Ashkenazi Jewish Crohn's disease suggests novel susceptibility loci.
Risk Allele T
P-val 2E-11
Odds Ratio 1.3700 None


[PMID 18438406OA-icon.png] Genetic determinants of ulcerative colitis include the ECM1 locus and five loci implicated in Crohn's disease.


[PMID 19140132OA-icon.png] Unbiased estimation of odds ratios: combining genomewide association scans with replication studies.


GET Evidence
rs9292777
aa_change
aa_change_short
impact pathogenic
qualified_impact Insufficiently evaluated pathogenic
overall_frequency 0.578125
summary