Have questions? Visit https://www.reddit.com/r/SNPedia

rs9303542

From SNPedia

Orientationplus
Stabilizedplus
Geno Mag Summary
(A;A) 0
(A;G) 1.1 1.1x increased risk for ovarian cancer
(G;G) 1.2 1.2x increased risk for ovarian cancer
ReferenceGRCh38 38.1/141
Chromosome17
Position48334138
GeneSKAP1
is asnp
is mentioned by
dbSNPrs9303542
ebirs9303542
HLIrs9303542
Exacrs9303542
Varsomers9303542
Maprs9303542
PheGenIrs9303542
hapmaprs9303542
1000 genomesrs9303542
hgdprs9303542
ensemblrs9303542
gopubmedrs9303542
geneviewrs9303542
scholarrs9303542
googlers9303542
pharmgkbrs9303542
gwascentralrs9303542
openSNPrs9303542
23andMers9303542
23andMe allrs9303542
SNP Nexus

SNPshotrs9303542
SNPdbers9303542
MSV3drs9303542
GWAS Ctlgrs9303542
GMAF0.3108
Max Magnitude1.2
rs9303542 is a SNP on chromosome 17q21, located in the intron of src kinase associated phosphoprotein 1 SKAP1 gene.

A genome-wide association study ultimately including over 10,000 ovarian cancer patients found statistically strong (p = 1.4 × 10e-7) evidence for slightly elevated risk associated with the rs9303542(G) allele, with an odds ratio of 1.14 (CI: 1.09–1.20) as calculated for the serous subtype (of ovarian cancer).[PMID 20852632OA-icon.png]

? (A;A) (A;G) (G;G) 28
GWAS snp
PMID [PMID 20852632OA-icon.png]
Trait
Title A genome-wide association study identifies susceptibility loci for ovarian cancer at 2q31 and 8q24
Risk Allele G
P-val 0.000001
Odds Ratio 1.11 [1.06-1.16]

[PMID 22253144OA-icon.png] Ovarian cancer susceptibility alleles and risk of ovarian cancer in BRCA1 and BRCA2 mutation carriers.

GWAS snp
PMID [PMID 23535730OA-icon.png]
Trait Ovarian cancer
Title GWAS meta-analysis and replication identifies three new susceptibility loci for ovarian cancer.
Risk Allele
P-val 6E-9
Odds Ratio 1.12 [1.08-1.16]

[PMID 25173882OA-icon.png] Replication Study for the Association of Seven Genome- Gwas-Identified Loci With Susceptibility to Ovarian Cancer in the Polish Population