Have questions? Visit https://www.reddit.com/r/SNPedia


From SNPedia

Make rs9344(A;A)
Make rs9344(A;G)
Make rs9344(G;G)
ReferenceGRCh38 38.1/141
is asnp
is mentioned by
1000 genomesrs9344
23andMe allrs9344
SNP Nexus

GWAS Ctlgrs9344
Merged fromRs17852153, Rs603965
Max Magnitude
? (A;A) (A;G) (G;G) 28

[PMID 20680537] Distribution of CCND1 A870G Polymorphism in Patients with Advanced Uterine Cervical Carcinoma

[PMID 21268129] Association of cyclin D1 gene polymorphisms with risk of esophageal squamous cell carcinoma in Kashmir Valley-A high risk area

[PMID 21723269] Genetic profiling of GSTP1, DPYD, FCGR2A, FCGR3A and CCND1 genes in an Argentinian population

[PMID 21890746OA-icon.png] Effects of ERCC2 Lys751Gln (A35931C) and CCND1 (G870A) polymorphism on outcome of advanced-stage squamous cell carcinoma of the head and neck are treatment dependent

[PMID 14724163OA-icon.png] Analysis of candidate modifier loci for the severity of colonic familial adenomatous polyposis, with evidence for the importance of the N-acetyl transferases.

[PMID 16465622OA-icon.png] Bladder cancer predisposition: a multigenic approach to DNA-repair and cell-cycle-control genes.

[PMID 16783567] Cyclin D1 splice variant and risk for non-Hodgkin lymphoma.

[PMID 18174243OA-icon.png] Association of single-nucleotide polymorphisms in the cell cycle genes with breast cancer in the British population.

[PMID 18507837OA-icon.png] Effects of common germline genetic variation in cell cycle control genes on breast cancer survival: results from a population-based cohort.

[PMID 18547414OA-icon.png] Genotyping panel for assessing response to cancer chemotherapy.

[PMID 19124506OA-icon.png] Common genetic variation in candidate genes and susceptibility to subtypes of breast cancer.

[PMID 19183483OA-icon.png] Screening and association testing of common coding variation in steroid hormone receptor co-activator and co-repressor genes in relation to breast cancer risk: the Multiethnic Cohort.

[PMID 19258477OA-icon.png] Candidate gene analysis using imputed genotypes: cell cycle single-nucleotide polymorphisms and ovarian cancer risk.

[PMID 19287456OA-icon.png] Cyclin D1b protein expression in breast cancer is independent of cyclin D1a and associated with poor disease outcome.

[PMID 19336552OA-icon.png] Risk of non-Hodgkin lymphoma associated with germline variation in genes that regulate the cell cycle, apoptosis, and lymphocyte development.

[PMID 19372140OA-icon.png] EGFR pathway polymorphisms and bladder cancer susceptibility and prognosis.

[PMID 19543528OA-icon.png] Association between common germline genetic variation in 94 candidate genes or regions and risks of invasive epithelial ovarian cancer.

[PMID 19585495] Association of HLA-DRB1, interleukin-6 and cyclin D1 polymorphisms with cervical cancer in the Swedish population--a candidate gene approach.

[PMID 19750108OA-icon.png] Decreased PM10 exposure attenuates age-related lung function decline: genetic variants in p53, p21, and CCND1 modify this effect.

[PMID 19941161] Combined genetic effect of CDK7 and ESR1 polymorphisms on breast cancer.

[PMID 21161398] Cyclin D1 G870A polymorphism and breast cancer risk: a meta-analysis comprising 9,911 cases and 11,171 controls.

[PMID 21273603] Significant association of cyclin D1 single nucleotide polymorphisms with oral cancer in taiwan.

[PMID 21594903] CCND1 rs9344 polymorphisms are associated with the genetic susceptibility to cervical cancer in Chinese population.

[PMID 21965784] Interaction of CCND1 genotype and smoking habit in Taiwan lung cancer patients.

[PMID 22399638] Association of cyclin D1 genotypes with nasopharyngeal carcinoma risk.

[PMID 23072573OA-icon.png] Multiplex Allele-Specific Amplification from Whole Blood for Detecting Multiple Polymorphisms Simultaneously

GET Evidence
impact not reviewed
qualified_impact Insufficiently evaluated not reviewed
overall_frequency 0.384737

[PMID 23125009] Significance of cyclin D1 polymorphisms in patients with head and neck cancer.

[PMID 23311506] The association of a variant in the cell cycle control gene CCND1 and obesity on the development of asthma in the Swiss SAPALDIA study.

[PMID 23354566] Prognostic significance of cyclin D1 polymorphisms on prostate-specific antigen recurrence after radical prostatectomy.

[PMID 23567490] The cyclin D1 (CCND1) rs9344 G>A polymorphism predicts clinical outcome in colon cancer patients treated with adjuvant 5-FU-based chemotherapy.

[PMID 23625573] A common and functional gene variant in the vascular endothelial growth factor a predicts clinical outcome in early-stage breast cancer.

Risk rs9344(A;A)
Alt rs9344(A;A)
Reference rs9344(G;G)
Significance Other
Disease Colorectal cancer VON HIPPEL-LINDAU SYNDROME
Variation info
Gene CCND1
CLNDBN Colorectal cancer, susceptibility to VON HIPPEL-LINDAU SYNDROME, MODIFIER OF
Reversed 0
HGVS NC_000011.9:g.69462910G>A
CLNSRC OMIM Allelic Variant
CLNACC RCV000014762.4, RCV000087019.4,

[PMID 26550182] Lack of association between cyclin D1 A870G (rs9344) polymorphism and esophageal squamous cell carcinoma risk: case-control study and meta-analysis