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rs9379896

From SNPedia

Orientationplus
Stabilizedplus
Make rs9379896(C;C)
Make rs9379896(C;T)
Make rs9379896(T;T)
ReferenceGRCh38 38.1/141
Chromosome6
Position10886716
GeneSYCP2L
is asnp
is mentioned by
dbSNPrs9379896
ebirs9379896
HLIrs9379896
Exacrs9379896
Varsomers9379896
Maprs9379896
PheGenIrs9379896
hapmaprs9379896
1000 genomesrs9379896
hgdprs9379896
ensemblrs9379896
gopubmedrs9379896
geneviewrs9379896
scholarrs9379896
googlers9379896
pharmgkbrs9379896
gwascentralrs9379896
openSNPrs9379896
23andMers9379896
23andMe allrs9379896
SNP Nexus

SNPshotrs9379896
SNPdbers9379896
MSV3drs9379896
GWAS Ctlgrs9379896
GMAF0.2227
Max Magnitude
? (C;C) (C;T) (T;T) 28
rs9379896 is a SNP on chromosome 6.

A case control study of ~2,000 women found that each rs9379896(C) allele was associated with an average increase in age at menopause of ~1 month. This also meant that each rs9379896(T) allele yielded an odds ratio of 1.13 (CI: 1.01–1.27, p = 3.8 x 10e-2) of early menopause, defined as occurring before the age of 46.[PMID 20952801OA-icon.png]

Overall, women homozygous for the "early" alleles at all 4 SNPs found in this study were ~4 times more likely to undergo menopause early compared to women who had a total of 3 or less risk alleles. However, the ability to predict which women will actually undergo early menopause using these 4 SNPs is still low.[PMID 20952801OA-icon.png]