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rs9472817(C;C)

From SNPedia

CC genotype increases risk of Alzheimer's in epsilon 4s.
Is agenotype
ofrs9472817
GeneLOC101926934, SLC25A27
Chromosome6
Position46,673,255
mentionedby
Magnitude2.1
ReputeBad
Geno Mag Summary
(C;C) 2.1 CC genotype increases risk of Alzheimer's in epsilon 4s.
(C;G) 2.1 CG genotype increases Alzheimer's risk relative to GG in epsilon 4s
(G;G) 2.1 Reduces risk of Alzheimer's in those with epsilon 4

The article on the SNP page noted that those with CC and APOE epsilon 4 had increased risk of Alzheimer's as compared with those only with epsilon 4. This result will need to be confirmed in a larger study. Also it is not clear what the implications are for those with homozygous epsilon 4 genotype.