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rs9472817(C;G)

From SNPedia

CG genotype increases Alzheimer's risk relative to GG in epsilon 4s
Is agenotype
ofrs9472817
GeneLOC101926934, SLC25A27
Chromosome6
Position46,673,255
mentionedby
Magnitude2.1
ReputeBad
Geno Mag Summary
(C;C) 2.1 CC genotype increases risk of Alzheimer's in epsilon 4s.
(C;G) 2.1 CG genotype increases Alzheimer's risk relative to GG in epsilon 4s
(G;G) 2.1 Reduces risk of Alzheimer's in those with epsilon 4

The risk of AD among those carrying an epsilon 4 and heterozygote gentotype at rs9472817 was intermediate between the other two homozygous genotypes. In the study cited for this SNP no specific p value is given for this heterozygote zygote result, though the CG genotype when considered in conjunction with epsilon 4 carriage yielded a p-value of p=1.02 * 10-13.