|?|| (A;A) (A;G) (G;G) ||28|
has been reported in a large study to be associated with rheumatoid arthritis
The risk allele (oriented to the dbSNP entry) is (A); the odds ratio associated with heterozygotes is 1.34 (CI 1.15-1.56), and for homozygotes, 2.23 (CI 1.21-4.13). [PMID 17554300]
[PMID 18794857] Rheumatoid arthritis susceptibility loci at chromosomes 10p15, 12q13 and 22q13.
[PMID 20017963] Representation of genetic association via attributable familial relative risks in order to identify polymorphisms functionally relevant to rheumatoid arthritis.