|?|| (A;A) (A;C) (C;C) ||28|
, also known as SG13S32, is an ALOX5AP
gene SNP that has been defined as part of a haplotype potentially associated with risk for myocardial infarction
or ischemic stroke
. Details of this haplotype and several related studies are on the ALOX5AP
[PMID 19130089] Genetic effects in the leukotriene biosynthesis pathway and association with atherosclerosis.
[PMID 19361804] 5-Lipoxygenase activating protein (ALOX5AP) gene variants associate with the presence of xanthomas in familial hypercholesterolemia.
[PMID 19751821] Oxidative risk for atherothrombotic cardiovascular disease.
[PMID 20067482] The role of LTA4H and ALOX5AP genes in the risk for asthma in Latinos.
[PMID 20810156] ALOX5AP and LTA4H polymorphisms modify augmentation of bronchodilator responsiveness by leukotriene modifiers in Latinos.
[PMID 24368493] Interaction between ALOX5AP and CYP3A5 gene variants significantly increases the risk for cerebral infarctions in Chinese
[PMID 24485247] Ischemic stroke risk in a southeastern Chinese population: Insights from 5-lipoxygenase activating protein and phosphodiesterase 4D single-nucleotide polymorphisms
[PMID 26885075] A tagging ALOX5AP polymorphism and risk of ischemic stroke in a northeastern Chinese Han population.