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rs9623117

From SNPedia

Orientationplus
Stabilizedplus
Geno Mag Summary
(C;C) 1.1x increased risk for prostate cancer
(C;T) 1.1x increased risk for prostate cancer
(T;T) normal
ReferenceGRCh38 38.1/141
Chromosome22
Position40056115
GeneTNRC6B
is asnp
is mentioned by
dbSNPrs9623117
ebirs9623117
HLIrs9623117
Exacrs9623117
Varsomers9623117
Maprs9623117
PheGenIrs9623117
hapmaprs9623117
1000 genomesrs9623117
hgdprs9623117
ensemblrs9623117
gopubmedrs9623117
geneviewrs9623117
scholarrs9623117
googlers9623117
pharmgkbrs9623117
gwascentralrs9623117
openSNPrs9623117
23andMers9623117
23andMe allrs9623117
SNP Nexus

SNPshotrs9623117
SNPdbers9623117
MSV3drs9623117
GWAS Ctlgrs9623117
GMAF0.3058
Max Magnitude
? (C;C) (C;T) (T;T) 28
[PMID 19117981OA-icon.png] In seven different populations studied, rs9623117(C) was consistently higher in aggressive prostate cancer cases than in controls (p = 5.0 x 10e-7). The odds ratio (OR) of allele C for aggressive prostate cancer was estimated to be 1.18 (CI: 1.11-1.26). This SNP was also associated with increased risk for nonaggressive prostate cancer, with an odds ratio of 1.11 (CI: 1.04 - 1.19, p = 0.004).



[PMID 19434657OA-icon.png] Individual and cumulative effect of prostate cancer risk-associated variants on clinicopathologic variables in 5,895 prostate cancer patients.


[PMID 19549807OA-icon.png] Prostate cancer risk associated loci in African Americans.


[PMID 20690139] Meta-analysis of genome-wide and replication association studies on prostate cancer.


GET Evidence
rs9623117
aa_change
aa_change_short
impact pathogenic
qualified_impact Insufficiently evaluated pathogenic
overall_frequency 0.40625
summary



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[PMID 26203264] Single nucleotide polymorphisms of microRNA processing genes and outcome of non-Hodgkin's lymphoma