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rs966221

From SNPedia

Orientationminus
Stabilizedminus
Geno Mag Summary
(C;C) 1.5 1.5x increased stroke risk certain populations
(C;T) 1.5x increased stroke risk
(T;T) 0 normal
ReferenceGRCh38 38.1/141
Chromosome5
Position60206693
GenePDE4D
is asnp
is mentioned by
dbSNPrs966221
ebirs966221
HLIrs966221
Exacrs966221
Varsomers966221
Maprs966221
PheGenIrs966221
hapmaprs966221
1000 genomesrs966221
hgdprs966221
ensemblrs966221
gopubmedrs966221
geneviewrs966221
scholarrs966221
googlers966221
pharmgkbrs966221
gwascentralrs966221
openSNPrs966221
23andMers966221
23andMe allrs966221
SNP Nexus

SNPshotrs966221
SNPdbers966221
MSV3drs966221
GWAS Ctlgrs966221
GMAF0.4922
Max Magnitude1.5
? (C;C) (C;T) (T;T) 28

[PMID 18694398] A study of 639 Chinese stroke patients concluded that the rs966221(C) allele is associated with increased risk for atherothrombotic strokes (odds ratio 1.51, CI: 1.09-2.10) in this population.


[PMID 21677445] Meta-Analysis of Homogeneous Subgroups Reveals Association between PDE4D Gene Variants and Ischemic Stroke


[PMID 16130105OA-icon.png] Phosphodiesterase 4D and 5-lipoxygenase activating protein in ischemic stroke.


[PMID 16166573] Association of phosphodiesterase 4D gene with ischemic stroke in a Pakistani population.


[PMID 16835261OA-icon.png] Phosphodiesterase 4D polymorphisms and the risk of cerebral infarction in a biracial population: the Stroke Prevention in Young Women Study.


[PMID 19409523OA-icon.png] Multilocus Bayesian meta-analysis of gene-disease associations.


[PMID 20031584OA-icon.png] Genetics of atherothrombotic and lacunar stroke.


[PMID 20540798OA-icon.png] Sex-differential genetic effect of phosphodiesterase 4D (PDE4D) on carotid atherosclerosis.


[PMID 23786009] [Association of rs966221 phosphodiesterase 4D gene's polymorphism with risk of myocardial infarction]


[PMID 23774910] [Association study between PDE4D gene polymorphism and ischemic stroke].