Have questions? Visit https://www.reddit.com/r/SNPedia

rs968567

From SNPedia

Orientationminus
Stabilizedplus
Make rs968567(A;A)
Make rs968567(A;G)
Make rs968567(G;G)
ReferenceGRCh38 38.1/142
Chromosome11
Position61828092
GeneFADS2
is asnp
is mentioned by
dbSNPrs968567
ebirs968567
HLIrs968567
Exacrs968567
Varsomers968567
Maprs968567
PheGenIrs968567
hapmaprs968567
1000 genomesrs968567
hgdprs968567
ensemblrs968567
gopubmedrs968567
geneviewrs968567
scholarrs968567
googlers968567
pharmgkbrs968567
gwascentralrs968567
openSNPrs968567
23andMers968567
23andMe allrs968567
SNP Nexus

SNPshotrs968567
SNPdbers968567
MSV3drs968567
GWAS Ctlgrs968567
GMAF0.07943
Max Magnitude
One of 42 more SNPs associated with rheumatoid arthritis based on a meta-analysis of 30,000 patients, most with odds ratios of 1.01 - 1.2. 10.1038/nature12873
? (A;A) (A;G) (G;G) 28
[PMID 19546342OA-icon.png] A common FADS2 promoter polymorphism increases promoter activity and facilitates binding of transcription factor ELK1


[PMID 20427696OA-icon.png] Single nucleotide polymorphisms in the FADS gene cluster are associated with delta-5 and delta-6 desaturase activities estimated by serum fatty acid ratios.


[PMID 20565855OA-icon.png] Genetic variation in lipid desaturases and its impact on the development of human disease.


[PMID 21383846OA-icon.png] Genetic variants of the FADS gene cluster and ELOVL gene family, colostrums LC-PUFA levels, breastfeeding, and child cognition.


[PMID 22877655OA-icon.png] Umbilical cord PUFA are determined by maternal and child fatty acid desaturase (FADS) genetic variants in the Avon Longitudinal Study of Parents and Children (ALSPAC)


[PMID 23285256OA-icon.png] Prostatic alpha-linolenic acid (ALA) is positively associated with aggressive prostate cancer: a relationship which may depend on genetic variation in ALA metabolism

GWAS snp
PMID [PMID 24390342OA-icon.png]
Trait Rheumatoid arthritis
Title Genetics of rheumatoid arthritis contributes to biology and drug discovery.
Risk Allele C
P-val 2E-8
Odds Ratio 1.12 [1.07-1.16]
GWAS snp
PMID [PMID 24816252OA-icon.png]
Trait Blood metabolite levels
Title An atlas of genetic influences on human blood metabolites.
Risk Allele T
P-val 2E-21
Odds Ratio .03 [0.025-0.041] unit increase