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rs9864422

From SNPedia

Orientationplus
Stabilizedplus
Geno Mag Summary
(C;C) 0 normal
(C;T) 1.45x increased osteoarthritis risk
(T;T) 1.45x increased osteoarthritis risk
ReferenceGRCh38 38.1/141
Chromosome3
Position15185745
GeneCOL6A4P1
is asnp
is mentioned by
dbSNPrs9864422
ebirs9864422
HLIrs9864422
Exacrs9864422
Varsomers9864422
Maprs9864422
PheGenIrs9864422
hapmaprs9864422
1000 genomesrs9864422
hgdprs9864422
ensemblrs9864422
gopubmedrs9864422
geneviewrs9864422
scholarrs9864422
googlers9864422
pharmgkbrs9864422
gwascentralrs9864422
openSNPrs9864422
23andMers9864422
23andMe allrs9864422
SNP Nexus

SNPshotrs9864422
SNPdbers9864422
MSV3drs9864422
GWAS Ctlgrs9864422
GMAF0.247
Max Magnitude0
? (C;C) (C;T) (T;T) 28
rs9864422 is one of several SNPs in the DVWA gene found to be associated with osteoarthritis based on a study of several Japanese patient populations. The allelic odds ratio is 1.45 (CI: 1.27-1.66, p = 3.4 x 10e-8) for the minor allele, which is the (T) allele (in dbSNP orientation). [PMID 18622395]
OMIM612401
Desc
Variant
Relatedalso


[PMID 20238217] Lack of evidence for association between DVWA gene polymorphisms and developmental dysplasia of the hip in Chinese Han population

[PMID 19181678] Large replication study and meta-analyses of DVWA as an osteoarthritis susceptibility locus in European and Asian populations.