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rs987237

From SNPedia

Orientationplus
Stabilizedplus
Make rs987237(A;A)
Make rs987237(A;G)
Make rs987237(G;G)
ReferenceGRCh38 38.1/141
Chromosome6
Position50835337
GeneTFAP2B
is asnp
is mentioned by
dbSNPrs987237
ebirs987237
HLIrs987237
Exacrs987237
Varsomers987237
Maprs987237
PheGenIrs987237
hapmaprs987237
1000 genomesrs987237
hgdprs987237
ensemblrs987237
gopubmedrs987237
geneviewrs987237
scholarrs987237
googlers987237
pharmgkbrs987237
gwascentralrs987237
openSNPrs987237
23andMers987237
23andMe allrs987237
SNP Nexus

SNPshotrs987237
SNPdbers987237
MSV3drs987237
GWAS Ctlgrs987237
GMAF0.1841
Max Magnitude
? (A;A) (A;G) (G;G) 28
GWAS snp
PMID [PMID 19557161OA-icon.png]
Trait Adiposity
Title Genome-Wide Association Scan Meta-Analysis Identifies Three Loci Influencing Adiposity and Fat Distribution
Risk Allele G
P-val 2E-11
Odds Ratio 0.04 [0.03-0.05] z-score unit increase
GWAS snp
PMID [PMID 20935630OA-icon.png]
Trait
Title Association analyses of 249,796 individuals reveal 18 new loci associated with body mass index
Risk Allele G
P-val 3E-20
Odds Ratio 0.13 [0.07-0.19] kg/m2 increase


[PMID 21686128OA-icon.png] Novel abdominal adiposity genes and the risk of type 2 diabetes: findings from two prospective cohorts


[PMID 19336370OA-icon.png] Determination of genetic predisposition to patent ductus arteriosus in preterm infants.


[PMID 22041983] Recapitulation of genome-wide association studies on body mass index in the Korean population.


[PMID 24670271] Association study of common polymorphisms in MSRA, TFAP2B, MC4R, NRXN3, PPARGC1A, TMEM18, SEC16B, HOXB5 and OLFM4 genes with obesity-related traits among Portuguese children.


GET Evidence
rs987237
aa_change
aa_change_short
impact pathogenic
qualified_impact Insufficiently evaluated pathogenic
overall_frequency 0.140625
summary



[PMID 23036851] Treatment factors rather than genetic variation determine metabolic syndrome in childhood cancer survivors

GWAS snp
PMID [PMID 23563607OA-icon.png]
Trait Body mass index
Title Genome-wide meta-analysis identifies 11 new loci for anthropometric traits and provides insights into genetic architecture.
Risk Allele G
P-val 2E-11
Odds Ratio 1.20 [NR]


[PMID 23471855OA-icon.png] The genetics of childhood obesity and interaction with dietary macronutrients.


[PMID 24081236] TFAP2B -dietary protein and glycemic index interactions and weight maintenance after weight loss in the DiOGenes trial