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rs9929218

From SNPedia

Orientationplus
Stabilizedplus
Make rs9929218(A;A)
Make rs9929218(A;G)
Make rs9929218(G;G)
ReferenceGRCh38 38.1/141
Chromosome16
Position68787043
GeneCDH1
is asnp
is mentioned by
dbSNPrs9929218
ebirs9929218
HLIrs9929218
Exacrs9929218
Varsomers9929218
Maprs9929218
PheGenIrs9929218
hapmaprs9929218
1000 genomesrs9929218
hgdprs9929218
ensemblrs9929218
gopubmedrs9929218
geneviewrs9929218
scholarrs9929218
googlers9929218
pharmgkbrs9929218
gwascentralrs9929218
openSNPrs9929218
23andMers9929218
23andMe allrs9929218
SNP Nexus

SNPshotrs9929218
SNPdbers9929218
MSV3drs9929218
GWAS Ctlgrs9929218
GMAF0.2475
Max Magnitude
? (A;A) (A;G) (G;G) 28
nature colorectal cancer

rs9929218, CDH1; P = 1.2 times 10-8)

GWAS snp
PMID [PMID 19011631OA-icon.png]
Trait Colorectal cancer
Title Meta-analysis of genome-wide association data identifies four new susceptibility loci for colorectal cancer
Risk Allele A
P-val 1E-8
Odds Ratio 1.10 [1.06-1.12]
OMIM612590
DescCOLORECTAL CANCER, SUSCEPTIBILITY TO, 9; CRCS9
Variant
Relatedalso



[PMID 20638935] Susceptibility Genetic Variants Associated With Colorectal Cancer Risk Correlate With Cancer Phenotype


[PMID 21119214OA-icon.png] Colorectal Cancer Susceptibility Loci in a Population-Based Study: Associations with Morphological Parameters


[PMID 22367214OA-icon.png] Characterization of gene-environment interactions for colorectal cancer susceptibility loci


[PMID 22363440OA-icon.png] cis-Expression QTL Analysis of Established Colorectal Cancer Risk Variants in Colon Tumors and Adjacent Normal Tissue


[PMID 18683894OA-icon.png] AXIN2 and CDH1 polymorphisms, tooth agenesis, and oral clefts.


[PMID 19639606OA-icon.png] Correcting "winner's curse" in odds ratios from genomewide association findings for major complex human diseases.


[PMID 20501757OA-icon.png] Low-penetrance susceptibility variants in familial colorectal cancer.


[PMID 20648012OA-icon.png] Association studies on 11 published colorectal cancer risk loci.


[PMID 21071539OA-icon.png] Generalizability and epidemiologic characterization of eleven colorectal cancer GWAS hits in multiple populations.


[PMID 21314996OA-icon.png] Systematic search for enhancer elements and somatic allelic imbalance at seven low-penetrance colorectal cancer predisposition loci.


[PMID 22045029] Relationship between 16 susceptibility loci and colorectal cancer phenotype in 3146 patients.


[PMID 22235025] Susceptibility genetic variants associated with early-onset colorectal cancer.


GET Evidence
rs9929218
aa_change
aa_change_short
impact pathogenic
qualified_impact Insufficiently evaluated pathogenic
overall_frequency 0.242188
summary



[PMID 23359760OA-icon.png] Single-nucleotide polymorphism associations for colorectal cancer in southern chinese population


[PMID 23114982] Genome-wide investigation of gene-environment interactions in colorectal cancer


[PMID 23712746] GENETIC SUSCEPTIBILITY VARIANTS ASSOCIATED WITH COLORECTAL CANCER PROGNOSIS


[PMID 22848671OA-icon.png] Association of eleven common, low-penetrance colorectal cancer susceptibility genetic variants at six risk loci with clinical outcome.


[PMID 22999960OA-icon.png] Much of the genetic risk of colorectal cancer is likely to be mediated through susceptibility to adenomas.


[PMID 23434150OA-icon.png] Are the common genetic variants associated with colorectal cancer risk for DNA mismatch repair gene mutation carriers?


[PMID 24838934OA-icon.png] Nucleotide variants of the cancer predisposing gene CDH1 and the risk of non-syndromic cleft lip with or without cleft palate


[PMID 24875374OA-icon.png] Variation in the Association Between Colorectal Cancer Susceptibility Loci and Colorectal Polyps by Polyp Type


[PMID 25873087] Analyses of 7,635 patients with colorectal cancer using independent training and validation cohorts show that rs9929218 in CDH1 is a prognostic marker of survival