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rs9940128

From SNPedia

Orientationplus
Stabilizedplus
Make rs9940128(A;A)
Make rs9940128(A;G)
Make rs9940128(G;G)
ReferenceGRCh38 38.1/141
Chromosome16
Position53766842
GeneFTO
is asnp
is mentioned by
dbSNPrs9940128
ebirs9940128
HLIrs9940128
Exacrs9940128
Varsomers9940128
Maprs9940128
PheGenIrs9940128
hapmaprs9940128
1000 genomesrs9940128
hgdprs9940128
ensemblrs9940128
gopubmedrs9940128
geneviewrs9940128
scholarrs9940128
googlers9940128
pharmgkbrs9940128
gwascentralrs9940128
openSNPrs9940128
23andMers9940128
23andMe allrs9940128
SNP Nexus

SNPshotrs9940128
SNPdbers9940128
MSV3drs9940128
GWAS Ctlgrs9940128
GMAF0.3508
Max Magnitude
? (A;A) (A;G) (G;G) 28

This SNP is in a linkage block in the FTO gene with rs1121980; see rs1121980 for the association of this block with early onset obesity since it showed the strongest association.[PMID 18159244OA-icon.png]

Neighborrs9939973
Distance186
Neighborrs1421085
Distance200
GWAS snp
PMID [PMID 22399527OA-icon.png]
Trait
Title Genome-wide screen for metabolic syndrome susceptibility Loci reveals strong lipid gene contribution but no evidence for common genetic basis for clustering of metabolic syndrome traits.
Risk Allele A
P-val 2E-9
Odds Ratio 0.0900 None


[PMID 18379722OA-icon.png] Variations in the FTO gene are associated with severe obesity in the Japanese.


[PMID 18599522OA-icon.png] FTO variants are associated with obesity in the Chinese and Malay populations in Singapore.


[PMID 20017965OA-icon.png] Identifying association under a previous linkage peak on chromosome 16 for body mass index using cross-sectional and longitudinal data of the Framingham Heart Study.


[PMID 21175269] Genetic variations in the FTO gene are associated with type 2 diabetes and obesity in south Indians (CURES-79).

GWAS snp
PMID [PMID 23669352OA-icon.png]
Trait Body mass index
Title Genome-wide analysis of BMI in adolescents and young adults reveals additional insight into the effects of genetic loci over the life course.
Risk Allele A
P-val 4E-23
Odds Ratio .08 [0.067-0.099] unit increase