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SULT1A1

From SNPedia

is agene
is mentioned by
Full namesulfotransferase family, cytosolic, 1A, phenol-preferring, member 1
EntrezGene6817
PheGenI6817
VariationViewer6817
ClinVarSULT1A1
GeneCardsSULT1A1
dbSNP6817
SADR6817
HugeNav6817
wikipediaSULT1A1
googleSULT1A1
gopubmedSULT1A1
EVSSULT1A1
HEFalMpSULT1A1
MyGene2SULT1A1
23andMeSULT1A1
UniProtP50225
EnsemblENSG00000196502
OMIM171150
# SNPs8
 Max MagnitudeChromosome positionSummary
rs104215728,605,736
rs180103028,606,164
rs196875228,620,264
rs28374453028,606,092
rs376009128,609,479
rs683928,605,807
rs75015528,609,251
rs928286128,606,193

Entrez Gene summary for SULT1A1 Gene:

Sulfotransferase enzymes catalyze the sulfate conjugation of many hormones, neurotransmitters, drugs, and xenobiotic compounds. These cytosolic enzymes are different in their tissue distributions and substrate specificities. The gene structure (number and length of exons) is similar among family members. This gene encodes one of two phenol sulfotransferases with thermostable enzyme activity. Multiple alternatively spliced variants that encode two isoforms have been identified for this gene. (provided by RefSeq, Jul 2008)

GeneCards Summary for SULT1A1 Gene [1]:

SULT1A1 (sulfotransferase family, cytosolic, 1A, phenol-preferring, member 1) is a protein-coding gene. Diseases associated with SULT1A1 include breast cancer susceptibility, and male breast cancer. GO annotations related to this gene include sulfotransferase activity and flavonol 3-sulfotransferase activity. An important paralog of this gene is SULT1C3.

UniProtKB/Swiss-Prot: ST1A1_HUMAN, P50225 Function:

Sulfotransferase that utilizes 3'-phospho-5'-adenylyl sulfate (PAPS) as sulfonate donor to catalyze the sulfate conjugation of catecholamines, phenolic drugs and neurotransmitters. Has also estrogen sulfotransferase activity. responsible for the sulfonation and activation of minoxidil. Is Mediates the metabolic activation of carcinogenic N-hydroxyarylamines to DNA binding products and could so participate as modulating factor of cancer risk

PharmGKB "VIP" summary for SULT1A1