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From SNPedia

User:SFBrown wrote: This information is not correct. See http://www.snpedia.com/index.php/Rs1799945 for details and correct information.

However he has not responded to a request for more info, and User:Lennon and I have been unable to figure out what was not correct. --- cariaso 19:14, 2 October 2014 (UTC)

2 x rs1799945 or rs1799945 + rs1800562 is not likely to result in symptoms of hemochromatosis[edit]

From 23andme: "The H63D mutation is very common ... This mutation only causes symptoms, though, when found in combination with the more severe C282Y mutation. Only a very small fraction of individuals with one copy of H63D and one copy of C282Y will exhibit evidence of iron overload in blood tests and symptoms, if they develop at all, are typically mild. Having two copies of H63D is not typically sufficient to cause symptoms."

H63D = rs1799945(G) C282Y = rs1800562(A)

If this is correct then it would be better to say "Potentially affected" rather than "Likely affected" in the lede description for this genoset.