In human mitochondrial genetics, Haplogroup H3 is a Human mitochondrial DNA haplogroup|human mitochondrial DNA (mtDNA) haplogroup descended from Haplogroup H (mtDNA). Mitochondria in humans is a double-stranded circular molecule of 16,569 base pairs. H3 is the next most common sub-haplogroup after H1, characterized by the polymorphism T6776C; a basepair in the coding region from locations numbered from 575 to 16,000. H3 is European, without Near Eastern representatives. H3 is ?9000 [Range 6,000 to 12,000] years old based on the coding-region data. H3 is ?11,000 years old [Range 8,000 to 14,000] using locations numbered 16001-16568 of the Hypervariable region HVR1.
Genome Res. 2005 January; 15(1): 19–24.doi: 10.1101/gr.3182305 PMCID: PMC540273 Copyright © 2005, Cold Spring Harbor Laboratory Press, High-resolution mtDNA evidence for the late-glacial resettlement of Europe from an Iberian refugium Luísa Pereira,1 Martin Richards,2 Ana Goios,1 Antonio Alonso,3 Cristina Albarrán,3 Oscar Garcia,4 Doron M. Behar,5 Mukaddes Gölge,6 Ji?i Hatina,7 Lihadh Al-Gazali,8 Daniel G. Bradley,9 Vincent Macaulay,10,12 and António Amorim1, http://www.ncbi.nlm.nih.gov/pmc/articles/PMC540273/ http://www.ncbi.nlm.nih.gov/pmc/articles/PMC540273/pdf/00150019.pdf