| | Max Magnitude | Chromosome position | Summary |
|---|
| i5004969 | | | |
| i5004970 | | | |
| i5004971 | | | |
| i5004972 | | | |
| i5004974 | | | |
| i5004975 | | | |
| i5994973 | | | |
| rs10431923 | 0 | 68,805,360 | |
| rs10431924 | 0 | 68,805,399 | |
| rs1057517542 | 0 | 68,829,653 | |
| rs1060501214 | 0 | 68,810,205 | |
| rs1060501215 | 0 | 68,801,883 | |
| rs1060501224 | 0 | 68,822,184 | |
| rs1060501226 | 0 | 68,738,295 | |
| rs1060501237 | 0 | 68,811,861 | |
| rs1060501244 | 0 | 68,828,204 | |
| rs1060501248 | 0 | 68,829,682 | |
| rs1064794230 | 0 | 68,808,525 | |
| rs1064795267 | 0 | 68,815,760 | |
| rs1064795703 | 0 | 68,801,821 | |
| rs116093741 | 5 | 68,812,144 | |
| rs11642413 | 0 | 68,756,491 | |
| rs12185157 | 0 | 68,750,684 | |
| rs121964871 | 0 | 68,823,593 | |
| rs121964872 | 0 | 68,833,362 | |
| rs121964873 | 6.7 | 68,810,290 | |
| rs121964874 | 6.7 | 68,823,557 | |
| rs121964875 | 5 | 68,738,307 | |
| rs121964876 | 6.7 | 68,738,318 | |
| rs121964877 | 6.7 | 68,822,081 | |
| rs121964878 | 5 | 68,822,190 | |
| rs12597188 | 0 | 68,780,923 | |
| rs13689 | 0 | 68,834,619 | |
| rs16260 | 0 | 68,737,131 | |
| rs16958383 | 0 | 68,823,097 | |
| rs17690554 | 0 | 68,835,607 | |
| rs17715799 | 0 | 68,796,608 | |
| rs1801026 | 0 | 68,833,553 | |
| rs1801552 | 0 | 68,823,538 | |
| rs1862748 | 0 | 68,799,040 | |
| rs202115589 | 0 | 68,819,424 | |
| rs267606712 | 6.7 | 68,811,859 | |
| rs28372783 | 0 | 68,737,219 | |
| rs33935154 | 0 | 68,822,138 | |
| rs35572355 | 5 | 68,833,344 | |
| rs370345996 | 0 | 68,829,757 | |
| rs376152506 | 0 | 68,801,888 | |
| rs4783573 | 0 | 68,806,685 | |
| rs4783673 | 0 | 68,758,190 | |
| rs4783689 | 0 | 68,819,768 | |
The CDH1 gene encodes the cadherin-1 protein, also known as CAM 120/80 or epithelial cadherin (E-cadherin). It is a tumor suppressor gene, and mutations in this gene have been associated with various cancers including breast cancer and hereditary diffuse gastric cancer.
Mutations considered pathogenic and acting in a dominant manner for gastric cancer, hereditary cancer-predisposing syndrome and related cancers include:
| rsid
|
23andMe term
|
synonyms (c. or p.)
|
OMIM
|
On chip?
|
| rs572272864
|
|
c.-63C>A
|
|
|
| rs749591910
|
|
c.48+5G>C
|
|
|
| rs121964875
|
i5004971
|
c.59G>A
|
192090.0009
|
Ancestry v2, Ancestry v2c, Ancestry v2d
|
| rs786203576
|
i5004970
|
c.60G>A
|
|
|
| rs121964876
|
i5004972
|
c.70G>T
|
192090.0011
|
Ancestry v2, Ancestry v2d
|
| rs786201058
|
|
c.76G>T
|
|
|
| rs876658865
|
|
c.124_126delCCCinsT
|
|
|
| rs786203727
|
|
c.185G>T
|
|
|
| rs587783047
|
|
c.187C>T
|
|
Ancestry v2, 23andMe v5, Ancestry v2c, Ancestry v2d
|
| rs786202151
|
|
c.202delT
|
|
23andMe v5, Ancestry v2c, Ancestry v2d
|
| rs781409616
|
|
c.283C>T
|
|
|
| rs587782677
|
|
c.353C>G
|
|
Ancestry v2, Ancestry v2d
|
| rs746703615
|
|
c.377delC
|
|
|
| rs376152506
|
|
c.382delC
|
|
|
| rs864622655
|
|
c.504delA
|
|
Ancestry v2c, Ancestry v2d
|
| rs587780537
|
|
c.715G>A
|
|
Ancestry v2, 23andMe v5, Ancestry v2c, Ancestry v2d
|
| rs587780784
|
|
c.1003C>T
|
|
23andMe v5, Ancestry v2c, Ancestry v2d
|
| rs267606712
|
|
c.1008G>T
|
192090.0005
|
Ancestry v2, Ancestry v2c, Ancestry v2d
|
| rs786201045
|
|
c.1009_1010delAG
|
|
|
| rs116093741
|
i5004975
|
c.1018A>G
|
192090.0016
|
Ancestry v2, Ancestry v2d
|
| rs587776398
|
|
c.1023T>G
|
|
Ancestry v2c, Ancestry v2d
|
| rs863224505
|
|
c.1063delT
|
|
Ancestry v2c, Ancestry v2d
|
| rs869312764
|
|
c.1064delT
|
|
|
| rs587782359
|
|
c.1118C>T
|
|
Ancestry v2, 23andMe v5, Ancestry v2c, Ancestry v2d
|
| rs587783050
|
|
c.1137G>A
|
|
Ancestry v2, 23andMe v5, Ancestry v2c, Ancestry v2d
|
| rs876660771
|
|
c.1137+1G>A
|
|
23andMe v5, Ancestry v2c, Ancestry v2d
|
| rs587782798
|
|
c.1147C>T
|
|
Ancestry v2, 23andMe v5, Ancestry v2c, Ancestry v2d
|
| rs876659208
|
|
c.1476_1477delAG
|
|
|
| rs876658261
|
|
c.1488_1494delCGAGGAC
|
|
|
| rs869312765
|
|
c.1505delG
|
|
|
| rs587780113
|
|
c.1565+1G>T
|
|
Ancestry v2c, Ancestry v2d
|
| rs587780113
|
|
c.1565+1G>A
|
|
Ancestry v2c, Ancestry v2d
|
| rs730881667
|
|
c.1610delC
|
|
Ancestry v2, Ancestry v2c, Ancestry v2d
|
| rs202115589
|
|
c.1710delT
|
|
Ancestry v2c, Ancestry v2d
|
| rs786202290
|
|
c.1711+5G>A
|
|
23andMe v5, Ancestry v2c, Ancestry v2d
|
| rs121964877
|
i5994973
|
c.1792C>T
|
192090.0012
|
Ancestry v2, Ancestry v2c, Ancestry v2d
|
| rs121964878
|
i5004974
|
c.1901C>T
|
192090.0015
|
Ancestry v2, Ancestry v2d
|
| rs587782750
|
|
c.1921C>T
|
|
Ancestry v2, 23andMe v5, Ancestry v2c, Ancestry v2d
|
| rs730881653
|
|
c.1979dupT
|
|
Ancestry v2, 23andMe v5, Ancestry v2c, Ancestry v2d
|
| rs786202033
|
|
c.1999delC
|
|
Ancestry v2c, Ancestry v2d
|
| rs587781276
|
|
c.2064_2065delTG
|
|
23andMe v5
|
| rs121964874
|
i5004969
|
c.2095C>T
|
192090.0007
|
Ancestry v2, Ancestry v2c, Ancestry v2d
|
| rs776975632
|
|
c.2245C>T
|
|
|
| rs587780787
|
|
c.2287G>T
|
|
Ancestry v2, 23andMe v5, Ancestry v2c, Ancestry v2d
|
| rs754162869
|
|
c.2310delC
|
|
|
| rs587780119
|
|
c.2343A>T
|
|
|
| rs587781335
|
|
c.2396C>G
|
|
Ancestry v2, Ancestry v2c, Ancestry v2d
|
| rs587783048
|
|
c.2398delC
|
|
Ancestry v2, 23andMe v5, Ancestry v2c, Ancestry v2d
|
| rs370345996
|
|
c.2399delG
|
|
Ancestry v2, Ancestry v2c, Ancestry v2d
|
| rs786203752
|
|
c.2430delT
|
|
23andMe v5
|
| rs35572355
|
rs35572355
|
c.2494G>A
|
192090.0017
|
23andMe v4, Ancestry v2, 23andMe v5, Ancestry v2c, 23andMe v3, 23andMe v1, Ancestry v2d
|
