DHFR
From SNPedia
| is a | gene |
| is | mentioned by |
| Full name | dihydrofolate reductase |
| Other names | DYR |
| EntrezGene | 1719 |
| PheGenI | 1719 |
| VariationViewer | 1719 |
| ClinVar | DHFR |
| GeneCards | DHFR |
| dbSNP | 1719 |
| Diseases | DHFR |
| SADR | 1719 |
| HugeNav | 1719 |
| wikipedia | DHFR |
| DHFR | |
| gopubmed | DHFR |
| EVS | DHFR |
| HEFalMp | DHFR |
| MyGene2 | DHFR |
| 23andMe | DHFR |
| UniProt | P00374 |
| Ensembl | ENSG00000228716 |
| OMIM | 126060 |
| # SNPs | 8 |
| Max Magnitude | Chromosome position | Summary | |
|---|---|---|---|
| rs121913223 | 0 | 80,633,904 | |
| rs1643649 | 0 | 80,643,630 | |
| rs1643659 | 0 | 80,639,017 | |
| rs1650697 | 0 | 80,654,962 | |
| rs1677693 | 0 | 80,640,499 | |
| rs387906619 | 0 | 80,649,393 | |
| rs70991108 | 1.5 | 80,654,344 | |
| rs7387 | 0 | 80,628,972 |
DHFR converts 7,8 dihydrobiopterin (BH2) and folate to tetrahydrobiopterin (BH4).
"Inhibiting the DHFR gene could help prevent the growth of neoplastic cancerous cells, ordinary cells which develop into tumour cells, such as Prostate cancer cells." new summary of this nature article
