According to Wikipedia, "Dupuytren's contracture (also known as morbus Dupuytren, or Dupuytren's disease and slang terms 'Viking disease' or 'Celtic hand'), is a fixed flexion contracture of the hand due to a palmar fibromatosis, where the fingers bend towards the palm and cannot be fully extended (straightened). It is an inherited proliferative connective tissue disorder that involves the hand's palmar fascia. It is named after Baron Guillaume Dupuytren, the surgeon who described an operation to correct the affliction in the Lancet in 1831."
[PMID 28886342] This GWAS study of ~8,000 patients finds an additional 17 SNPs, each associated with (slightly) higher or lower risk for Dupuytren's disease, bringing the total to 26 identified variants. The SNP with the largest effect was rs16879765, for which the (T) allele was associated with an odds ratio of 1.9 (p = 3 x 10e-81).
[PMID 24573701]SNPs Previously Associated with Dupuytren's Disease Replicated in a North American Cohort.
[[https://www.ncbi.nlm.nih.gov/pubmed/22772327 ?dopt=Abstract PMID 22772327 ]]Whole genome and global expression profiling of Dupuytren's disease: systematic review of current findings and future perspectives.
[PMID 22448555][Dupuytren's contracture] Dupuytrenin kontraktuura.
[PMID 21732829]Wnt signaling and Dupuytren's disease. (GWAS study)
[PMID 20971583]Genome-wide association scan of Dupuytren's disease. (GWAS study)