FABP2
From SNPedia
is a | gene |
is | mentioned by |
EntrezGene | 2169 |
PheGenI | 2169 |
VariationViewer | 2169 |
ClinVar | FABP2 |
GeneCards | FABP2 |
dbSNP | 2169 |
Diseases | FABP2 |
SADR | 2169 |
HugeNav | 2169 |
wikipedia | FABP2 |
FABP2 | |
gopubmed | FABP2 |
EVS | FABP2 |
HEFalMp | FABP2 |
MyGene2 | FABP2 |
23andMe | FABP2 |
# SNPs | 4 |
Max Magnitude | Chromosome position | Summary | |
---|---|---|---|
i6010053 | |||
rs11724758 | 0 | 119,318,723 | |
rs1799883 | 0 | 119,320,747 | |
rs5861422 | 0 | 119,322,182 |
Half the U.S. population carries a gene variant which causes them to metabolize fat differently and may hurt their ability to remove sugar from the blood [1]. This difference is related to Diabetes.
[PMID 17209184] FABP2 Ala54Thr genotype is associated with glucoregulatory function and lipid oxidation after a high-fat meal in sedentary nondiabetic men and women. FABP2 Thr54 carriers have lower glucose tolerance and lower insulin action than do Ala54-homozygous persons. Furthermore, FABP Thr54 carriers have higher lipid oxidation rates, which may be the mechanism of glucoregulatory dysfunction.