GSTP1
From SNPedia
| is a | gene |
| is | mentioned by |
| Full name | glutathione S-transferase pi 1 |
| EntrezGene | 2950 |
| PheGenI | 2950 |
| VariationViewer | 2950 |
| ClinVar | GSTP1 |
| GeneCards | GSTP1 |
| dbSNP | 2950 |
| Diseases | GSTP1 |
| SADR | 2950 |
| HugeNav | 2950 |
| wikipedia | GSTP1 |
| GSTP1 | |
| gopubmed | GSTP1 |
| EVS | GSTP1 |
| HEFalMp | GSTP1 |
| MyGene2 | GSTP1 |
| 23andMe | GSTP1 |
| UniProt | P09211 |
| Ensembl | ENSG00000084207 |
| OMIM | 134660 |
| # SNPs | 13 |
| Max Magnitude | Chromosome position | Summary | |
|---|---|---|---|
| rs1138272 | 0 | 67,586,108 | |
| rs1695 | 2.1 | 67,585,218 | influences asthma risk |
| rs17593068 | 0 | 67,583,461 | |
| rs1871042 | 0 | 67,586,373 | |
| rs4147581 | 0 | 67,584,114 | |
| rs4891 | 0 | 67,586,499 | |
| rs6591255 | 0 | 67,582,077 | |
| rs6591256 | 0 | 67,582,428 | |
| rs749174 | 0 | 67,585,782 | |
| rs762803 | 0 | 67,584,785 | |
| rs8191439 | 0 | 67,583,826 | |
| rs947894 | 0 | 67,585,218 | |
| rs947895 | 0 | 67,586,935 |
The glutathione S-transferases (GSTs) are a family of enzymes that play an important role in detoxification by catalysing with reduced glutathione the conjugation of many hydrophobic and electrophilic compounds. Based on their biochemical, immunological, and structural properties, the soluble GSTs are categorized into 4 main classes: alpha, mu, pi, and theta. The GSTP1 member of the GST family is a polymorphic gene encoding active, functionally different GSTP1 variant proteins, which are believed to function in xenobiotic metabolism, and play a role in susceptibility to cancer and other diseases.
