Gastric cancer
Gastric cancer, also called stomach cancer, may cause up to 1 million deaths per year worldwide. In several countries it is the second largest cause of cancer deaths; more information is available at Wikipedia on the general topic. Although the most frequent correlation for increased gastric cancer risk is not genetic - it is infection by Helicobacter pylori - genetic predisposition may also play a role. [PMID 15854000] [PMID 17196954]
A SNP that is reported to be an independent risk factor for gastric cancer, and even higher risk in H. pylori-infected individuals, is:
SNPs that have been reported to increase the risk for developing gastric cancer include:
SNPs in the following genes have also been reported to increase gastric cancer risk:
