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Glimepiride

From SNPedia

Glimepiride (original trade name Amaryl) is an orally available medium-to-long-acting sulfonylurea antidiabetic drug. Glimepiride is indicated to treat type-2 diabetes; its mode of action is to increase insulin production by the pancreas. It is not used for type-1 diabetes because in type-1 diabetes the pancreas is not able to produce insulin.Wikipedia

PGx Table for Glimepiride (Amaryl)
Genotype/Genoset Diplotype Gene Drug Use/Category/Class Medical Field Summary Descriptive Sentence
gs309 WT/WT G6PD Diabetes Endocrinology Normal Response Expected You do not appear to carry any G6PD mutations linked to an unwanted side effect (hemolytic anemia).
gs307 Carrier G6PD Diabetes Endocrinology Consider Alternatives You carry a G6PD mutation that might lead to an unwanted side effect (hemolytic anemia) when taking glimepiride; due to variable expression (i.e. in females), enzymatic testing for G6PD activity is advisable.
gs308 G6PD-deficient G6PD Diabetes Endocrinology Consider Alternatives You carry a G6PD mutation linked to an unwanted side effect (hemolytic anemia) when taking glimepiride; use caution and consider non-sulfonylurea alternatives.