| Variant of uncertain significance; possible Lynch syndrome mutation |
| Is a | genotype |
| of | rs267608073 |
| Gene | MSH6 |
| Chromosome | 2 |
| Position | 47,801,023 |
| mentioned | by |
| Magnitude | 5 |
| Repute | Bad |
| Geno | Mag | Summary |
|---|---|---|
| (-;AAG) | 5 | Variant of uncertain significance; possible Lynch syndrome mutation |
| (AAG;AAG) | 0 | common/normal |
Listed in ClinVar as being of uncertain significance, the minor allele of this genotype, causing an in-frame deletion, has been reported in individuals affected with colon, endometrial, and pancreatic cancer, but it has not been proven to be causative.
