MICA
From SNPedia
| is a | gene |
| is | mentioned by |
| Full name | MHC class I polypeptide-related sequence A |
| EntrezGene | 100507436 |
| PheGenI | 100507436 |
| VariationViewer | 100507436 |
| ClinVar | MICA |
| GeneCards | MICA |
| dbSNP | 100507436 |
| Diseases | MICA |
| SADR | 100507436 |
| HugeNav | 100507436 |
| wikipedia | MICA |
| MICA | |
| gopubmed | MICA |
| EVS | MICA |
| HEFalMp | MICA |
| MyGene2 | MICA |
| 23andMe | MICA |
| UniProt | Q29983 |
| Ensembl | ENSG00000204520 |
| OMIM | 600169 |
| # SNPs | 16 |
| Max Magnitude | Chromosome position | Summary | |
|---|---|---|---|
| rs1051792 | 0 | 31,411,200 | |
| rs1051794 | 0 | 31,411,332 | |
| rs1063635 | 0 | 31,412,154 | |
| rs114202986 | 0 | 31,408,140 | |
| rs114291795 | 0 | 31,409,863 | |
| rs12175489 | 0 | 31,409,810 | |
| rs2256183 | 0 | 31,412,752 | |
| rs2256184 | 0 | 31,412,806 | |
| rs2301747 | 0 | 31,403,810 | |
| rs2596538 | 0 | 31,400,855 | |
| rs2596542 | 0 | 31,398,818 | |
| rs2848716 | 0 | 31,420,190 | |
| rs3128982 | 0 | 31,449,414 | |
| rs3763288 | 0 | 31,402,590 | |
| rs4349859 | 3 | 31,398,010 | |
| rs4418214 | 0 | 31,423,624 |
The MICA gene encodes the highly polymorphic MHC class I polypeptide-related sequence A.Wikipedia
MICA is located within the human leukocyte antigen (HLA/MHC) locus, and its exon5 coding transmembrane (TM) region contains a polymorphic microsatellite, classified according to the number of alanine-encoding GCT repeats as A4, A5, A5.1, A6 and A9. A single nucleotide polymorphism (SNP) at codon 129 in exon 3 of the MICA gene, Val129Met or V129M (rs1051792), has been shown to modulate the affinity of MICA to the NKG2D receptor.
