Have questions? Visit https://www.reddit.com/r/SNPedia

OR7D4

From SNPedia
is agene
is mentioned by
Full nameolfactory receptor, family 7, subfamily D, member 4
EntrezGene125958
PheGenI125958
VariationViewer125958
ClinVarOR7D4
GeneCardsOR7D4
dbSNP125958
DiseasesOR7D4
SADR125958
HugeNav125958
wikipediaOR7D4
googleOR7D4
gopubmedOR7D4
EVSOR7D4
HEFalMpOR7D4
MyGene2OR7D4
23andMeOR7D4
UniProtQ8NG98
EnsemblENSG00000174667
OMIM611538
# SNPs4
 Max MagnitudeChromosome positionSummary
rs28783299,215,066
rs50202789,214,440
rs617299079,214,576


[PMID 17873857] Genetic variation in a human odorant receptor alters odour perception.
A common variant of the receptor OR7D4, OR7D4 WM contains two non-synonymous single nucleotide polymorphisms (SNPs), resulting in two amino acid substitutions (rs61729907 or R88W, and rs5020278 or T133M; hence 'RT') that severely impair function in vitro. Human subjects with RT/WM or WM/WM genotypes as a group were less sensitive to androstenone and androstadienone and found both odours less unpleasant than the RT/RT group.