Rasburicase, sold under trade names including Elitek, Fasturtec, and Rasuritek, is a medication that helps to clear uric acid from the blood.Wikipedia A pegylated form of rasburicase, pegloticase, is also FDA-approved for the treatment of refractory gout.
|Genotype/Genoset||Diplotype||Gene||Drug Use/Category/Class||Medical Field||Summary||Descriptive Sentence|
|gs309||WT/WT||G6PD||Leukemia; Gout||Oncology; Rheumatology||Normal Response Expected||You do not appear to carry any G6PD mutations linked to an unwanted side effect (hemolytic anemia and methemoglobinemia).|
|gs307||Carrier||G6PD||Leukemia; Gout||Oncology; Rheumatology||Use with Caution||You carry a G6PD mutation that might lead to an unwanted side effect (hemolytic anemia and methemoglobinemia) when taking rasburicase; due to variable expression (i.e. in females), enzymatic testing for G6PD activity is advisable.|
|gs308||G6PD-deficient||G6PD||Leukemia; Gout||Oncology; Rheumatology||Avoid Use||You carry a G6PD mutation linked to an unwanted side effect (hemolytic anemia and methemoglobinemia) when taking rasburicase; rasburicaseshould not be prescribed for you according to the FDA.|